Use of Human Monocyte-Derived Macrophages to Study Neisseria gonorrhoeae Infection.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9496-0_18
Abstract: Macrophages are critical cells in the innate immune response to microorganisms sensed in the tissues. During infections, the interaction between pathogens and macrophages leads to a macrophage response that includes cytokine production, antigen processing and… read more here.
Keywords: response; infection; human monocyte; neisseria gonorrhoeae ... See more keywords
siRNA-based identification of IBD-related targets in human monocyte-derived dendritic cells.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of immunological methods"
DOI: 10.1016/j.jim.2021.113058
Abstract: Inflammatory bowel disease (IBD) is thought to be caused by an aberrant host response to the commensal enteric flora in genetically susceptible individuals. Dendritic cells (DCs) play a key role in the regulation of this… read more here.
Keywords: response; sirna based; human monocyte; dendritic cells ... See more keywords
The development and function of human monocyte-derived dendritic cells regulated by metabolic reprogramming.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of leukocyte biology"
DOI: 10.1093/jleuko/qiad062
Abstract: Human monocyte-derived dendritic cells (moDCs) develop from monocytes play a key role in innate inflammatory responses as well as T-cell priming. Steady-state moDCs regulate immunogenicity and tolerogenicity by changing metabolic patterns to participate in the… read more here.
Keywords: derived dendritic; monocyte derived; metabolic reprogramming; dendritic cells ... See more keywords
Evaluation of recombinant factor C assay for the detection of divergent lipopolysaccharide structural species and comparison with Limulus amebocyte lysate‐based assays and a human monocyte activity assay
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Medical Microbiology"
DOI: 10.1099/jmm.0.000510
Abstract: Purpose. The Limulus amebocytelysate (LAL) assay is widely used for the screening of lipopolysaccharide (LPS) in parenteral pharmaceuticals. However, correlation of LPS in Gram‐negative bacterial infections by LAL assay has been problematic, partly due to… read more here.
Keywords: monocyte activity; based assays; human monocyte; assays human ... See more keywords
Human Monocyte Heterogeneity as Revealed by High-Dimensional Mass Cytometry
Sign Up to like & getrecommendations! Published in 2019 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvbaha.118.311022
Abstract: Objective— Three distinct human monocyte subsets have been identified based on the surface marker expression of CD14 and CD16. We hypothesized that monocytes were likely more heterogeneous in composition. Approach and Results— We used the… read more here.
Keywords: monocyte subsets; mass cytometry; monocyte heterogeneity; cad ... See more keywords
The homozygous CX3CR1-M280 mutation impairs human monocyte survival.
Sign Up to like & getrecommendations! Published in 2018 at "JCI insight"
DOI: 10.1172/jci.insight.95417
Abstract: Several reports have demonstrated that mouse Cx3cr1 signaling promotes monocyte/macrophage survival. In agreement, we previously found that, in a mouse model of systemic candidiasis, genetic deficiency of Cx3cr1 resulted in increased mortality and impaired tissue… read more here.
Keywords: m280; cx3cr1 m280; human monocyte; cx3cr1 ... See more keywords
Human Monocyte Subsets and Phenotypes in Major Chronic Inflammatory Diseases
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.02035
Abstract: Human monocytes are divided in three major populations; classical (CD14+CD16−), non-classical (CD14dimCD16+), and intermediate (CD14+CD16+). Each of these subsets is distinguished from each other by the expression of distinct surface markers and by their functions… read more here.
Keywords: major chronic; human monocytes; human monocyte; phenotypes major ... See more keywords
Phenotype and Response to PAMPs of Human Monocyte-Derived Foam Cells Obtained by Long-Term Culture in the Presence of oxLDLs
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.01592
Abstract: Cholesterol-laden, foam macrophages constitute the most characteristic component of human atherosclerotic plaques. Persistent uptake of oxLDLs results in accumulation of lipid bodies inside the cells and determines their phenotype and subsequent functions. In this work,… read more here.
Keywords: oxldls; human monocyte; derived foam; foam cells ... See more keywords
Argon Plasma Exposure Augments Costimulatory Ligands and Cytokine Release in Human Monocyte-Derived Dendritic Cells
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22073790
Abstract: Cold physical plasma is a partially ionized gas expelling many reactive oxygen and nitrogen species (ROS/RNS). Several plasma devices have been licensed for medical use in dermatology, and recent experimental studies suggest their putative role… read more here.
Keywords: plasma; human monocyte; plasma exposure; dendritic cells ... See more keywords
The Human Monocyte—A Circulating Sensor of Infection and a Potent and Rapid Inducer of Inflammation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23073890
Abstract: Monocytes were previously thought to be the precursors of all tissue macrophages but have recently been found to represent a unique population of cells, distinct from the majority of tissue macrophages. Monocytes and intestinal macrophages… read more here.
Keywords: monocyte circulating; tissue macrophages; potent; factor ... See more keywords
The Phagocytosis of Lacticaseibacillus casei and Its Immunomodulatory Properties on Human Monocyte-Derived Dendritic Cells Depend on the Expression of Lc-p75, a Bacterial Peptidoglycan Hydrolase
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23147620
Abstract: The human gut symbiont Lacticaseibacillus (L.) casei (previously Lactobacillus casei) is under intense research due to its wide range of immunomodulatory effects on the human host. Dendritic cells (DCs) are crucial players in the direct… read more here.
Keywords: lacticaseibacillus casei; phagocytosis; casei; monocyte derived ... See more keywords