Human monocytic myeloid‐derived suppressor cells impair B‐cell phenotype and function in vitro
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Immunology"
DOI: 10.1002/eji.201948240
Abstract: Myeloid‐derived suppressor cells (MDSCs) are key regulators of immunity that initially have been defined by their ability to potently suppress T‐cell responses. Recent studies collectively demonstrate that the suppressive activity of MDSCs is not limited… read more here.
Keywords: suppressor cells; derived suppressor; human monocytic; function ... See more keywords
Zika, dengue and yellow fever viruses induce differential anti‐viral immune responses in human monocytic and first trimester trophoblast cells
Sign Up to like & getrecommendations! Published in 2018 at "Antiviral Research"
DOI: 10.1016/j.antiviral.2018.01.003
Abstract: ABSTRACT Zika virus (ZIKV) is a mosquito‐borne flavivirus associated with severe neonatal birth defects, but the causative mechanism is incompletely understood. ZIKV shares sequence homology and early clinical manifestations with yellow fever virus (YFV) and… read more here.
Keywords: anti viral; yellow fever; human monocytic; immune responses ... See more keywords
Human Monocytic Ehrlichiosis, Mexico City, Mexico
Sign Up to like & getrecommendations! Published in 2020 at "Emerging Infectious Diseases"
DOI: 10.3201/eid2612.200520
Abstract: Little information is available about human infections by the members of the genus Ehrlichia in Mexico. Only 2 species, Ehrlichia canis and E. chaffensis, are known to cause disease in this country. We report a… read more here.
Keywords: human monocytic; mexico city; mexico; ehrlichiosis mexico ... See more keywords
Lysosomal Ca2+ Signaling Regulates High Glucose-Mediated Interleukin-1β Secretion via Transcription Factor EB in Human Monocytic Cells
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.01161
Abstract: Aberrant activation of the innate immune system, including NOD-like receptor pyrin domain containing 3 (NLRP3) inflammasome-dependent interleukin-1β (IL-1β) secretion, has been implicated in the pathogenesis of type 2 diabetes mellitus (T2DM) and its complication. Our… read more here.
Keywords: interleukin secretion; human monocytic; ca2; lysosomal ca2 ... See more keywords
Human Monocytic Suppressive Cells Promote Replication of Mycobacterium tuberculosis and Alter Stability of in vitro Generated Granulomas
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.02417
Abstract: Tuberculosis (TB) has tremendous public health relevance. It most frequently affects the lung and is characterized by the development of unique tissue lesions, termed granulomas. These lesions encompass various immune populations, with macrophages being most… read more here.
Keywords: human monocytic; vitro generated; tuberculosis; generated granulomas ... See more keywords
The Cooperative Induction of CCL4 in Human Monocytic Cells by TNF-α and Palmitate Requires MyD88 and Involves MAPK/NF-κB Signaling Pathways
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20184658
Abstract: Chronic low-grade inflammation, also known as metabolic inflammation, is a hallmark of obesity and parallels with the presence of elevated circulatory levels of free fatty acids and inflammatory cytokines/chemokines. CCL4/MIP-1β chemokine plays a key role… read more here.
Keywords: human monocytic; cooperative induction; ccl4; tnf palmitate ... See more keywords