Looking beyond the binary: an extended paradigm for focus of attention in human motor performance.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental brain research"
DOI: 10.1007/s00221-021-06126-4
Abstract: Focus of attention (FOA) has been shown to affect human motor performance. Research into FOA has mainly posited it as either external or internal to-the-body (EFOA and IFOA, respectively). However, this binary paradigm overlooks the… read more here.
Keywords: paradigm; human motor; motor; performance ... See more keywords
Reconsolidation of human motor memory: From boundary conditions to behavioral interventions—How far are we from clinical applications?
Sign Up to like & getrecommendations! Published in 2018 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2018.07.003
Abstract: The memory reconsolidation hypothesis states that a previously consolidated and stable memory can return to a temporary labile state after retrieved, requiring a new stabilization process. During the labile period, the memory trace is vulnerable… read more here.
Keywords: motor memory; boundary conditions; human motor; reconsolidation ... See more keywords
Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition
Sign Up to like & getrecommendations! Published in 2021 at "Stem Cell Reports"
DOI: 10.1016/j.stemcr.2021.03.029
Abstract: Summary Neuromuscular junctions (NMJs) ensure communication between motor neurons (MNs) and muscle; however, in MN disorders, such as amyotrophic lateral sclerosis (ALS), NMJs degenerate resulting in muscle atrophy. The aim of this study was to… read more here.
Keywords: hdac6 inhibition; microfluidic devices; human motor; fus mutations ... See more keywords
Distributed representation of pelvic floor muscles in human motor cortex
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-25705-0
Abstract: Human motor cortex can activate pelvic floor muscles (PFM), but the motor cortical representation of the PFM is not well characterized. PFM representation is thought to be focused in the supplementary motor area (SMA). Here… read more here.
Keywords: human motor; pfm; motor; motor cortex ... See more keywords
Image-based deep learning reveals the responses of human motor neurons to stress and VCP-related ALS.
Sign Up to like & getrecommendations! Published in 2021 at "Neuropathology and applied neurobiology"
DOI: 10.1111/nan.12770
Abstract: OBJECTIVES Although morphological attributes of cells and their substructures are recognized readouts of physiological or pathophysiological states, these have been relatively understudied in amyotrophic lateral sclerosis (ALS) research. MATERIALS AND METHODS In this study, we… read more here.
Keywords: image based; motor neurons; human motor; deep learning ... See more keywords
Separability of Human Motor Memories during reaching adaptation with force cues
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Computational Biology"
DOI: 10.1371/journal.pcbi.1009966
Abstract: Judging by the breadth of our motor repertoire during daily activities, it is clear that acquiring multiple motor skills is a hallmark of the human motor system. However, for reaching movements the different planning conditions… read more here.
Keywords: human motor; reaching adaptation; motor; force ... See more keywords
Neurofilament Light Regulates Axon Caliber, Synaptic Activity, and Organelle Trafficking in Cultured Human Motor Neurons
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.820105
Abstract: Neurofilament light (NFL) is one of the proteins forming multimeric neuron-specific intermediate filaments, neurofilaments, which fill the axonal cytoplasm, establish caliber growth, and provide structural support. Dominant missense mutations and recessive nonsense mutations in the… read more here.
Keywords: motor neurons; human motor; organelle trafficking; patient specific ... See more keywords
Internal Mechanisms of Human Motor Behaviour: A System-Theoretical Perspective
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Psychology"
DOI: 10.3389/fpsyg.2022.841343
Abstract: The authors present the conceptual and system-theoretical model of human motor behaviour. The main assumption is that movement is the only observable manifestation of all psychical processes, thus, it is the only phenomenon enabling the… read more here.
Keywords: system; human motor; system theoretical; motor ... See more keywords
Aryl Hydrocarbon Receptor (AhR)-Mediated Signaling in iPSC-Derived Human Motor Neurons
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15070828
Abstract: Exposure to environmental pollutants and endogenous metabolites that induce aryl hydrocarbon receptor (AhR) expression has been suggested to affect cognitive development and, particularly in boys, also motor function. As current knowledge is based on epidemiological… read more here.
Keywords: motor neurons; human motor; ahr ligands; expression ... See more keywords