Articles with "human murine" as a keyword



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GABAergic signaling in human and murine NK cells upon challenge with Toxoplasma gondii

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Published in 2021 at "Journal of Leukocyte Biology"

DOI: 10.1002/jlb.3hi0720-431r

Abstract: Protective cytotoxic and proinflammatory cytokine responses by NK cells impact the outcome of infections by Toxoplasma gondii, a common parasite in humans and other vertebrates. However, T. gondii can also sequester within NK cells and… read more here.

Keywords: gaba; toxoplasma gondii; human murine; gondii ... See more keywords
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Efficacy of novel selective NLRP3 inhibitors in human and murine retinal pigment epithelial cells

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Published in 2019 at "Journal of Molecular Medicine"

DOI: 10.1007/s00109-019-01753-5

Abstract: NLRP3 inflammasome activation in the retinal pigment epithelium (RPE) is observed in atrophic age-related macular degeneration (AMD), and pharmacological NLRP3 inhibition may provide a therapeutic strategy to halt disease progression. We tested selective NLRP3 inhibitors… read more here.

Keywords: human murine; inflammasome activation; nlrp3 inhibitors; activation ... See more keywords

Transplantation sites for human and murine islets

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Published in 2017 at "Diabetologia"

DOI: 10.1007/s00125-017-4362-8

Abstract: Aims/hypothesisBeta cell replacement is a potential cure for type 1 diabetes. In humans, islet transplants are currently infused into the liver via the portal vein, although this site has disadvantages. Here, we investigated alternative transplantation… read more here.

Keywords: murine islets; human murine; muscle; portal vein ... See more keywords
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On the compressibility and poroelasticity of human and murine skin

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Published in 2019 at "Biomechanics and Modeling in Mechanobiology"

DOI: 10.1007/s10237-019-01129-1

Abstract: A total of 37 human and 33 murine skin samples were subjected to uniaxial monotonic, cyclic, and relaxation experiments. Detailed analysis of the three-dimensional kinematic response showed that skin volume is significantly reduced as a… read more here.

Keywords: compressibility poroelasticity; human murine; murine skin; poroelasticity human ... See more keywords
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Human and murine fibroblast single cell transcriptomics reveals fibroblast clusters are differentially affected by ageing, and serum cholesterol.

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Published in 2023 at "Cardiovascular research"

DOI: 10.1093/cvr/cvad016

Abstract: AIMS Specific fibroblast markers and in-depth heterogeneity analysis are currently lacking, hindering functional studies in cardiovascular diseases (CVD). Here, we established cell-type markers and heterogeneity in murine and human arteries and studied the adventitial fibroblast… read more here.

Keywords: fibroblast; human murine; cell transcriptomics; single cell ... See more keywords
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Susceptibility of Human and Murine Dermal Fibroblasts to Herpes Simplex Virus 1 in the Absence and Presence of Extracellular Matrix

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Published in 2021 at "Journal of Virology"

DOI: 10.1128/jvi.02068-21

Abstract: Dermal fibroblasts are exposed to HSV-1 upon invasion in skin during in vivo infection. Thus, fibroblasts represent a widely used experimental tool to understand virus-host cell interactions and are highly susceptible in culture. ABSTRACT Herpes… read more here.

Keywords: dermis; dermal fibroblasts; human murine; infection ... See more keywords