Cautionary note on the use of Caenorhabditis elegans to study muscle phenotypes caused by mutations in the human MYH7 gene.
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DOI: 10.2144/btn-2020-0012
Abstract: Mutations in the human MYH7 gene, encoding a slow skeletal muscle/β-cardiac myosin heavy chain, cause different types of myopathies. The nematode model Caenorhabditis elegans has frequently been employed to study the molecular and physiological consequences… read more here.
Keywords: human myh7; muscle; mutations human; caenorhabditis elegans ... See more keywords