Bioengineered optogenetic model of human neuromuscular junction.
Sign Up to like & getrecommendations! Published in 2021 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2021.121033
Abstract: Functional human tissues engineered from patient-specific induced pluripotent stem cells (hiPSCs) hold great promise for investigating the progression, mechanisms, and treatment of musculoskeletal diseases in a controlled and systematic manner. For example, bioengineered models of… read more here.
Keywords: optogenetic model; model human; human neuromuscular; bioengineered optogenetic ... See more keywords
The Structure of Human Neuromuscular Junctions: Some Unanswered Molecular Questions
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DOI: 10.3390/ijms18102183
Abstract: The commands that control animal movement are transmitted from motor neurons to their target muscle cells at the neuromuscular junctions (NMJs). The NMJs contain many protein species whose role in transmission depends not only on… read more here.
Keywords: junctions unanswered; transmitter; human neuromuscular; structure ... See more keywords
Quantification of human neuromuscular function through optogenetics
Sign Up to like & getrecommendations! Published in 2019 at "Theranostics"
DOI: 10.7150/thno.25735
Abstract: The study of human neuromuscular diseases has traditionally been performed in animal models, due to the difficulty of performing studies in human subjects. Despite the unquestioned value of animal models, inter-species differences hamper the translation… read more here.
Keywords: quantification human; tissue; human neuromuscular; function optogenetics ... See more keywords