Impaired DNA double‐strand breaks repair by kinesin family member 4A inhibition renders human H1299 non‐small‐cell lung cancer cells sensitive to cisplatin
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27703
Abstract: Patients with non‐small‐cell lung cancer (NSCLC) are routinely treated with the platinum‐based chemotherapeutics such as cisplatin. The drug exerts anticancer effects via multiple mechanisms, including DNA double‐strand breaks (DSBs). Enhanced DNA DSB repair capacity would… read more here.
Keywords: cisplatin; nsclc cells; non small; small cell ... See more keywords
ESE‑1 suppresses the growth, invasion and migration of human NSCLC cells and tumor formation in vivo.
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DOI: 10.3892/or.2018.6560
Abstract: Lung cancer is the first leading cause of cancer‑related death in the United States. Non‑small cell lung cancer (NSCLC) is the most common type of lung cancer and is associated with a poor patient prognosis.… read more here.
Keywords: nsclc cells; ese expression; cancer; growth ... See more keywords