Human oocyte capacitation culture: Essential step toward hormone‐free assisted reproductive technology
Sign Up to like & getrecommendations! Published in 2025 at "Reproductive Medicine and Biology"
DOI: 10.1002/rmb2.12640
Abstract: In vitro oocyte maturation (IVM) is not a novel concept; however, its wide‐scale practice has been limited because of the lower clinical outcomes compared to conventional assisted reproductive technologies. read more here.
Keywords: human oocyte; culture essential; culture; assisted reproductive ... See more keywords
A pannexin 1 channelopathy causes human oocyte death
Sign Up to like & getrecommendations! Published in 2019 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.aav8731
Abstract: Inherited dominant mutations in PANX1 cause female infertility characterized by oocyte death. A vital gene for oocytes Infertility is common in both males and females, but the biological causes of female infertility are not as… read more here.
Keywords: death; pannexin; female infertility; human oocyte ... See more keywords
A novel heterozygous missense variant of PANX1 causes human oocyte death and female infertility
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DOI: 10.1186/s13048-024-01462-9
Abstract: Pannexin1 (PANX1) is a highly glycosylated membrane channel-forming protein, which has been found to implicate in multiple physiological and pathophysiological functions. Variants in the PANX1 gene have been reported to be associated with oocyte death… read more here.
Keywords: human oocyte; variant; panx1; novel heterozygous ... See more keywords
Clinical Application of Antioxidants to Improve Human Oocyte Mitochondrial Function: A Review
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DOI: 10.3390/antiox9121197
Abstract: Mitochondria produce adenosine triphosphate (ATP) while also generating high amounts of reactive oxygen species (ROS) derived from oxygen metabolism. ROS are small but highly reactive molecules that can be detrimental if unregulated. While normally functioning… read more here.
Keywords: improve human; mitochondrial function; human oocyte; review ... See more keywords