Daidzein stimulates osteogenesis facilitating proliferation, differentiation, and antiapoptosis in human osteoblast-like MG-63 cells via estrogen receptor-dependent MEK/ERK and PI3K/Akt activation.
Sign Up to like & getrecommendations! Published in 2017 at "Nutrition research"
DOI: 10.1016/j.nutres.2017.04.009
Abstract: Daidzein, a natural soy isoflavone, has a structure similar to estradiol and exhibiting bone-sparing effects against osteoporosis. However, the molecular mechanisms of osteogenesis remain unclear. We hypothesized that daidzein stimulates osteogenesis through estrogen receptor (ER)-dependent… read more here.
Keywords: daidzein stimulates; proliferation; human osteoblast; differentiation ... See more keywords
Regulation of Human Osteoblast-to-Osteocyte Differentiation by Direct-Write 3D Microperiodic Hydroxyapatite Scaffolds
Sign Up to like & getrecommendations! Published in 2019 at "ACS Omega"
DOI: 10.1021/acsomega.8b03272
Abstract: Culturing osteocytes on planer surfaces on Petri dish in vitro fails to recapitulate their natural orientation as well as biological functionality in human bone. Ability to recapitulate spatial arr... read more here.
Keywords: direct write; human osteoblast; regulation human; osteocyte differentiation ... See more keywords
Effects of Triiodothyronine on Human Osteoblast-Like Cells: Novel Insights From a Global Transcriptome Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.886136
Abstract: Background: Thyroid hormones play a significant role in bone development and maintenance, with triiodothyronine (T3) particularly being an important modulator of osteoblast differentiation, proliferation, and maintenance. However, details of the biological processes (BPs) and molecular… read more here.
Keywords: human osteoblast; triiodothyronine human; osteoblast like; effects triiodothyronine ... See more keywords
The Effects of Polyphenol, Tannic Acid, or Tannic Acid in Combination with Pamidronate on Human Osteoblast Cell Line Metabolism
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DOI: 10.3390/molecules27020451
Abstract: Background: This study investigates the effect of tannic acid (TA) combined with pamidronate (PAM) on a human osteoblast cell line. Methods: EC50 for TA, PAM, and different combination ratios of TA and PAM (25:75, 50:50,… read more here.
Keywords: human osteoblast; tannic acid; combination; pam ... See more keywords