Towards maturation of human otic hair cell-like cells in pluripotent stem cell-derived organoid transplants.
Sign Up to like & getrecommendations! Published in 2021 at "Cell and tissue research"
DOI: 10.1007/s00441-021-03510-y
Abstract: Human otic organoids generated from pluripotent stem cells (PSCs) provide a promising platform for modeling, drug testing, and cell-based therapies of inner ear diseases. However, providing the appropriate niche that resembles inner ear development and… read more here.
Keywords: otic organoids; human otic; pluripotent stem; maturation ... See more keywords
Generation of human otic neuronal organoids using pluripotent stem cells
Sign Up to like & getrecommendations! Published in 2023 at "Cell Proliferation"
DOI: 10.1111/cpr.13434
Abstract: Otic neurons, also known as spiral ganglion neurons (SGNs) in mammalian cochlea, transmit electrical signals from sensory hair cells to cochlear nuclei of the auditory system. SGNs are sensitive to toxic insults, vulnerable to get… read more here.
Keywords: otic neuronal; pluripotent stem; human otic; neuronal organoids ... See more keywords