The modulatory effect of green tea catechin on drug resistance in human ovarian cancer cells
Sign Up to like & getrecommendations! Published in 2019 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-019-02324-6
Abstract: AbstractNumerous in vitro and in vivo studies have demonstrated the antiproliferative effect of green tea. It has been speculated that one of its compounds — catechin, may affect multidrug resistance (MDR) phenomena. We examined the effect of… read more here.
Keywords: green tea; effect; drug; resistance ... See more keywords
Stably Fluorescent Cell Line of Human Ovarian Epithelial Cancer Cells SK-OV-3ip-red
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DOI: 10.1007/s10517-017-3933-5
Abstract: Stable red fluorescing line of human ovarian epithelial cancer cells SK-OV-3ip-red was generated expressing gene coding for protein TurboFP635 (Katushka) fluorescing in the far-red spectrum region with excitation and emission peaks at 588 and 635… read more here.
Keywords: line; ovarian epithelial; line human; human ovarian ... See more keywords
A novel fibrin-based artificial ovary prototype resembling human ovarian tissue in terms of architecture and rigidity
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-017-1091-3
Abstract: PurposeThe aim of this study is to optimize fibrin matrix composition in order to mimic human ovarian tissue architecture for human ovarian follicle encapsulation and grafting.MethodsUltrastructure of fresh human ovarian cortex in age-related women (n = 3)… read more here.
Keywords: fibrin; f50 t50; tissue; human ovarian ... See more keywords
Structure of constituents isolated from the bark of Cassipourea malosana and their cytotoxicity against a human ovarian cell line
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Natural Medicines"
DOI: 10.1007/s11418-018-1254-2
Abstract: Three aromatic compounds, 2α,3α-epoxyflavan-5,7,4′-triol-(4β → 8)-afzelechin (1), 2β,3β-epoxyflavan-5,7,4′-triol-(4α → 8)-epiafzelechin (2), and methyl 4-ethoxy-2-hydroxy-6-propylbenzoate (3), as well as eight known compounds (4–11) were isolated from the bark of Cassipourea malosana (Rhizophoraceae). Their structures were determined on the basis of… read more here.
Keywords: cassipourea malosana; cell line; bark cassipourea; human ovarian ... See more keywords
Ubiquitin-specific peptidase 39 regulates the process of proliferation and migration of human ovarian cancer via p53/p21 pathway and EMT
Sign Up to like & getrecommendations! Published in 2019 at "Medical Oncology"
DOI: 10.1007/s12032-019-1308-7
Abstract: Ovarian cancer is one of the most lethal gynecological cancers; owning to its late detection and chemoresistance, understanding the pathogenesis of this malignant tumor is much critical. Previous studies have reported that ubiquitin-specific peptidase 39… read more here.
Keywords: ubiquitin specific; migration; ovarian cancer; human ovarian ... See more keywords
The natural terthiophene α-terthienylmethanol induces S phase cell cycle arrest of human ovarian cancer cells via the generation of ROS stress.
Sign Up to like & getrecommendations! Published in 2017 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2017.05.011
Abstract: Ovarian cancer is the most lethal gynecological malignancy worldwide. Thiophenes such as terthiophene have been shown to have anti-tumor effects on several cancer cell lines, including ovarian cancer cells. However, the underlying mechanisms behind the… read more here.
Keywords: terthienylmethanol; human ovarian; arrest; ovarian cancer ... See more keywords
Light element distribution in fresh and frozen-thawed human ovarian tissues: a preliminary study.
Sign Up to like & getrecommendations! Published in 2018 at "Reproductive biomedicine online"
DOI: 10.1016/j.rbmo.2018.04.051
Abstract: RESEARCH QUESTION Does synchrotron X-ray fluorescence (XRF) provide novel chemical information for the evaluation of human ovarian tissue cryopreservation protocols? DESIGN Tissues from five patients undergoing laparoscopic surgery for benign gynaecological conditions were fixed for… read more here.
Keywords: microscopy; distribution; electron microscopy; cryopreservation ... See more keywords
Resveratrol supports and alpha‐naphthoflavone disrupts growth of human ovarian follicles in an in vitro tissue culture model
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2017.11.009
Abstract: ABSTRACT Infertility is a global health problem with an estimated incidence of 15%. Exposure to chemicals is a potential causal factor, and there is a lack of studies examining the effects on female germ cells.… read more here.
Keywords: tissue culture; tissue; ovarian follicles; human ovarian ... See more keywords
Stepped vitrification technique for human ovarian tissue cryopreservation
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DOI: 10.1038/s41598-019-56585-7
Abstract: The advantage of stepped vitrification (SV) is avoiding ice crystal nucleation, while decreasing the toxic effects of high cryoprotectant concentrations. We aimed to test this method for human ovarian tissue cryopreservation. Ovarian cortex was taken… read more here.
Keywords: ovarian tissue; tissue; tissue cryopreservation; stepped vitrification ... See more keywords
miR-214 promotes radioresistance in human ovarian cancer cells by targeting PETN
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DOI: 10.1042/bsr20170327
Abstract: Ovarian cancer is one of the leading causes of death among gynecological malignancies. Increasing evidence indicate that dysregulation of microRNAs (miRNAs) plays an important role in tumor radioresistance. The aim of the present study is… read more here.
Keywords: ovarian cancer; mir 214; human ovarian; cancer ... See more keywords
Repetitive Maturation of Oocytes From Non-Stimulated Xenografted Ovarian Tissue From a Prepubertal Patient Indicating the Independence of Human Ovarian Tissue
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DOI: 10.1055/s-0043-122601
Abstract: Introduction Modern anti-cancer strategies have distinctly increased survival rates; nevertheless, often accompanied by sterility. Currently, the only option for preserving fertility in prepubertal females is to cryopreserve ovarian tissue and re-transplant frozen-thawed tissue to restore… read more here.
Keywords: ovarian tissue; tissue; human ovarian; repetitive maturation ... See more keywords