Single‐cell RNA‐sequencing of retrieved human oocytes and eggs in clinical practice and for human ovarian cell atlasing
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23648
Abstract: With the advancement of single‐cell separation techniques and high‐throughput sequencing platforms, single‐cell RNA‐sequencing (scRNA‐seq) has emerged as a vital technology for understanding tissue and organ systems at cellular resolution. Through transcriptional analysis, it is possible… read more here.
Keywords: cell; rna sequencing; scrna seq; single cell ... See more keywords
Dynamics of WNT signaling components in the human ovary from development to adulthood
Sign Up to like & getrecommendations! Published in 2018 at "Histochemistry and Cell Biology"
DOI: 10.1007/s00418-018-1729-y
Abstract: WNT signaling has been shown to play a pivotal role in mammalian gonad development and sex differentiation; however, its role in the developing human ovary has not been investigated. We analyzed a quantitative mass spectrometry… read more here.
Keywords: wnt signaling; catenin; signaling components; human ovary ... See more keywords
A predictive model of the effect of therapeutic radiation on the human ovary
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0277052
Abstract: Radiation to the female pelvis as part of treatment for cancer predisposes young women to develop Premature Ovarian Insufficiency (POI). As the human female is born with their full complement of non-growing follicles which decline… read more here.
Keywords: age; fertility; human ovary; model ... See more keywords
11-Oxygenated androgens are not secreted by the human ovary: in-vivo data from four different cases of hyperandrogenism
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Endocrinology"
DOI: 10.1530/eje-22-0518
Abstract: Objective Differentiation of an adrenal from an ovarian source of hyperandrogenemia can be challenging. Recent studies have highlighted the importance of 11-oxygenated C19 steroids to the androgen pool in humans. The aim of this study… read more here.
Keywords: oxygenated androgens; different cases; four different; human ovary ... See more keywords
The Human Ovary and Future of Fertility Assessment in the Post-Genome Era
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DOI: 10.3390/ijms20174209
Abstract: Proteomics has opened up new avenues in the field of gynecology in the post-genome era, making it possible to meet patient needs more effectively and improve their care. This mini-review aims to reveal the scope… read more here.
Keywords: human ovary; genome era; post genome;