Articles with "human p2x4" as a keyword



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Identification of the molecular determinants of antagonist potency in the allosteric binding pocket of human P2X4

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Published in 2023 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2023.1101023

Abstract: P2X receptors are a family of ATP-gated cation channels comprising seven subtypes in mammals, which play key roles in nerve transmission, pain sensation and inflammation. The P2X4 receptor in particular has attracted significant interest from… read more here.

Keywords: bx430; allosteric pocket; pocket; human p2x4 ... See more keywords