Cryo-EM structures of the human PA200 and PA200-20S complex reveal regulation of proteasome gate opening and two PA200 apertures.
Sign Up to like & getrecommendations! Published in 2020 at "PLOS Biology"
DOI: 10.2210/pdb6kwy/pdb
Abstract: Proteasomes are highly abundant and conserved protease complexes that eliminate unwanted proteins in the cells. As a single-chain ATP-independent nuclear proteasome activator, proteasome activator 200 (PA200) associates with 20S core particle to form proteasome complex… read more here.
Keywords: pa200 20s; proteasome; cryo structures; pa200 ... See more keywords