A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas.
Sign Up to like & getrecommendations! Published in 2018 at "Cell systems"
DOI: 10.1016/j.cels.2018.07.007
Abstract: Understanding the genomic logic that underlies cellular diversity and developmental potential in the human pancreas will accelerate the growth of cell replacement therapies and reveal genetic risk mechanisms in diabetes. Here, we identified and characterized… read more here.
Keywords: risk; lineage; human pancreas; disease risk ... See more keywords
Hypothermic pulsatile perfusion of human pancreas: Preliminary technical feasibility study based on histology.
Sign Up to like & getrecommendations! Published in 2018 at "Cryobiology"
DOI: 10.1016/j.cryobiol.2018.10.002
Abstract: BACKGROUND There are currently two approaches to hypothermic preservation for most solid organs: static or dynamic. Cold storage is the main method used for static storage (SS), while hypothermic pulsatile perfusion (HPP) and other machine… read more here.
Keywords: perfusion; human pancreas; pulsatile perfusion; hypothermic pulsatile ... See more keywords
Gotta Have GATA for Human Pancreas Development.
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DOI: 10.1016/j.stem.2017.04.004
Abstract: Haploinsufficient GATA6 mutations are associated with human pancreatic agenesis. Shi et al. (2017) in this issue of Cell Stem Cell and Tiyaboonchai et al. (2017) in a recent issue of Cell Reports utilize hPSCs to characterize GATA6… read more here.
Keywords: got gata; human pancreas; pancreas development; gata human ... See more keywords
Extracellular matrix scaffold and hydrogel derived from decellularized and delipidized human pancreas
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-28857-1
Abstract: Extracellular matrix (ECM) plays an important developmental role by regulating cell behaviour through structural and biochemical stimulation. Tissue-specific ECM, attained through decellularization, has been proposed in several strategies for tissue and organ replacement. Decellularization of… read more here.
Keywords: matrix scaffold; hydrogel; human pancreas; extracellular matrix ... See more keywords
The best insulin delivery is a human pancreas
Sign Up to like & getrecommendations! Published in 2023 at "Clinical Transplantation"
DOI: 10.1111/ctr.14920
Abstract: We wanted to compare glycemic control post pancreas transplantation with newer therapeutic options. read more here.
Keywords: human pancreas; best insulin; insulin delivery; delivery human ... See more keywords
Bringing the human pancreas into focus: new paradigms for the understanding of Type 1 diabetes
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DOI: 10.1111/dme.13365
Abstract: Type 1 diabetes affects increasingly large numbers of people globally (including at least half a million children under the age of 14 years) and it remains an illness with life‐long and often devastating consequences. It… read more here.
Keywords: pancreas focus; human pancreas; type diabetes; focus new ... See more keywords