The leucine-rich repeat domain of human peroxidasin 1 promotes binding to laminin in basement membranes.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2020.108443
Abstract: Human peroxidasin 1 (PXDN) is a homotrimeric multidomain heme peroxidase and essential for tissue development and architecture. It has a biosynthetic function and catalyses the hypobromous acid-mediated formation of specific covalent sulfilimine (SN) bonds, which… read more here.
Keywords: leucine rich; repeat domain; human peroxidasin; basement membranes ... See more keywords
Human peroxidasin 1 promotes angiogenesis through ERK1/2, Akt, and FAK pathways
Sign Up to like & getrecommendations! Published in 2019 at "Cardiovascular Research"
DOI: 10.1093/cvr/cvy179
Abstract: Aims The term angiogenesis refers to sprouting of new blood vessels from pre-existing ones. The angiogenic process involves cell migration and tubulogenesis requiring interaction between endothelial cells and the extracellular matrix. Human peroxidasin 1 (hsPxd01)… read more here.
Keywords: akt fak; recombinant; peroxidasin; human peroxidasin ... See more keywords