Human Peroxisomal 3-Ketoacyl-CoA Thiolase: Tissue Expression and Metabolic Regulation : Human Peroxisomal Thiolase.
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DOI: 10.1007/978-3-030-60204-8_12
Abstract: This paper reports that the human peroxisomal 3-ketoacyl-CoA thiolase expression shows three transcripts: Tr1 (1705 bp), Tr2 (1375 bp) and Tr3 (1782 bp). Their highest expression is observed in the human liver and at a lesser extent in… read more here.
Keywords: human peroxisomal; regulation human; peroxisomal ketoacyl; expression ... See more keywords
Dynamics of the translocation pore of the human peroxisomal protein import machinery
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DOI: 10.1515/hsz-2022-0170
Abstract: Abstract Peroxisomal matrix proteins are synthesized on cytosolic ribosomes and imported in a posttranslational manner. Intricate protein import machineries have evolved that catalyze the different stages of translocation. In humans, PEX5L was found to be… read more here.
Keywords: translocation; protein import; protein; dynamics translocation ... See more keywords
Structural and functional insights of the human peroxisomal ABC transporter ALDP
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DOI: 10.7554/elife.75039
Abstract: Adrenoleukodystrophy protein (ALDP) is responsible for the transport of very-long-chain fatty acids (VLCFAs) and corresponding CoA-esters across the peroxisomal membrane. Dysfunction of ALDP leads to peroxisomal metabolic disorder exemplified by X-linked adrenoleukodystrophy (ALD). Hundreds of… read more here.
Keywords: functional insights; peroxisomal abc; insights human; abc transporter ... See more keywords