Combined diffusion‐relaxometry MRI to identify dysfunction in the human placenta
Sign Up to like & getrecommendations! Published in 2019 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.27733
Abstract: A combined diffusion‐relaxometry MR acquisition and analysis pipeline for in vivo human placenta, which allows for exploration of coupling between T2* and apparent diffusion coefficient (ADC) measurements in a sub 10‐minute scan time. read more here.
Keywords: diffusion relaxometry; combined diffusion; diffusion; human placenta ... See more keywords
Human Placenta Laminin-111 as a Multifunctional Protein for Tissue Engineering and Regenerative Medicine.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-0947-2_1
Abstract: Laminins are major components of all basement membranes surrounding nerve or vascular tissues. In particular laminin-111, the prototype of the family, facilitates a large spectrum of fundamental cellular responses in all eukaryotic cells. Laminin-111 is… read more here.
Keywords: laminin 111; medicine; tissue engineering; human placenta ... See more keywords
Alteration of Placental Deiodinase 3 Expression by BDE 209 and Possible Protection by Taurine in Human Placenta-Derived JEG Cells Under Hypoxia.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-8023-5_67
Abstract: Thyroid hormones are key hormones involved in growth and development. Changes in their levels can cause embryonic brain developmental damage in the first trimester. Studies have shown that polybrominated diphenyl ethers (PBDEs) have developmental neurotoxicity… read more here.
Keywords: derived jeg; human placenta; jeg cells; placenta derived ... See more keywords
Human placenta and trophoblast development: key molecular mechanisms and model systems
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-019-03104-6
Abstract: Abnormal placentation is considered as an underlying cause of various pregnancy complications such as miscarriage, preeclampsia and intrauterine growth restriction, the latter increasing the risk for the development of severe disorders in later life such… read more here.
Keywords: model systems; human placenta; placenta trophoblast; trophoblast ... See more keywords
Fetal Exosomal Platelet-activating Factor Triggers Functional Progesterone Withdrawal in Human Placenta
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive Sciences"
DOI: 10.1007/s43032-020-00283-7
Abstract: In most mammals, labor is heralded by the withdrawal of progesterone. In humans, circulating progesterone levels increase as gestation advances while placental expression of progesterone receptor A (PR-A) declines. As a result of PR-A downregulation,… read more here.
Keywords: platelet activating; labor; activating factor; human placenta ... See more keywords
Epigenetic states in the human placenta: A singular epigenome for an exceptional tissue.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental cell"
DOI: 10.1016/j.devcel.2021.04.011
Abstract: The placenta is a dynamic, short-lived organ, and many features of its epigenome are unique among human tissues. In this issue of Developmental Cell, Zhang et al. define new aspects of epigenetic regulation in normal and… read more here.
Keywords: epigenetic states; epigenome exceptional; placenta singular; human placenta ... See more keywords
Clarification and 3-D visualization of immunolabeled human placenta villi.
Sign Up to like & getrecommendations! Published in 2017 at "Placenta"
DOI: 10.1016/j.placenta.2017.03.015
Abstract: We report here the successful 3D visualization of human placenta villous structures on the order of ∼1 mm3 by a combination of immunolabeling, rapid tissue clarification and laser scanning confocal microscopy. The resultant image sets exhibit… read more here.
Keywords: clarification visualization; human placenta; villi; placenta ... See more keywords
Nutritional composition and heavy metal content of the human placenta.
Sign Up to like & getrecommendations! Published in 2017 at "Placenta"
DOI: 10.1016/j.placenta.2017.07.013
Abstract: Despite the vital and diverse roles of the placenta, remarkably little is known about its actual composition. Moreover, as placentophagy becomes increasingly popular, understanding the nutritional and heavy metal composition of the human placenta has… read more here.
Keywords: placenta nutritional; human placenta; composition; heavy metal ... See more keywords
SLC11A1 is expressed in the human placenta across multiple gestational ages.
Sign Up to like & getrecommendations! Published in 2019 at "Placenta"
DOI: 10.1016/j.placenta.2018.11.009
Abstract: The human placenta functions as an innate immune barrier to prevent fetal infection. However, the molecular mechanisms accounting for placental resistance to pathogens are currently poorly understood. The solute carrier family 11 member 1 (SLC11A1)… read more here.
Keywords: expressed human; multiple gestational; slc11a1 expressed; placenta ... See more keywords
Trimethylamine N-Oxide increases soluble fms-like tyrosine Kinase-1 in human placenta via NADPH oxidase dependent ROS accumulation.
Sign Up to like & getrecommendations! Published in 2020 at "Placenta"
DOI: 10.1016/j.placenta.2020.10.021
Abstract: BACKGROUNDS Preeclampsia (PE) is characterized as placental vascular disturbance and excessive secretion of soluble fms-like tyrosine kinase 1 (sFlt-1) into the maternal circulation. Trimethylamine N-oxide (TMAO, a gut microbe-derived metabolite) is strongly associated with various… read more here.
Keywords: hrt svneo; tmao; human placenta; trophoblasts hrt ... See more keywords
miR-15b-5p promotes expression of proinflammatory cytokines in human placenta by inhibiting Apelin signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Placenta"
DOI: 10.1016/j.placenta.2020.11.002
Abstract: INTRODUCTION The timing of parturition at end of human gestation may be controlled by fetal signals. The signaling molecules contributing to activation of human labor may be mediated by fetal exosomes. In this study, we… read more here.
Keywords: labor; apelin; mir; human placenta ... See more keywords