Isolation of Human Placental Mast Cells
Sign Up to like & getrecommendations! Published in 2018 at "Current Protocols in Cell Biology"
DOI: 10.1002/cpcb.52
Abstract: Mast cells have been identified as resident cells of human placental tissue by immunohistological procedures, suggesting that they may play a role in pregnancy. However, the study of placental mast cells requires their isolation. Here,… read more here.
Keywords: mast cells; mast; placental mast; isolation human ... See more keywords
Photoacoustic imaging of the human placental vasculature
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biophotonics"
DOI: 10.1002/jbio.201900167
Abstract: Abstract Minimally invasive fetal interventions require accurate imaging from inside the uterine cavity. Twin‐to‐twin transfusion syndrome (TTTS), a condition considered in this study, occurs from abnormal vascular anastomoses in the placenta that allow blood to… read more here.
Keywords: vasculature; photoacoustic imaging; imaging human; human placental ... See more keywords
Magnetically Responsive Polymeric Microparticles for the Triggered Delivery of a Complex Mixture of Human Placental Proteins.
Sign Up to like & getrecommendations! Published in 2020 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202000249
Abstract: Bone loss through traumatic injury is a significant clinical issue. Researchers have created many scaffold types to mimic an extracellular matrix to provide structural support for the formation of new bone, however functional regeneration of… read more here.
Keywords: magnetically responsive; placental proteins; delivery; human placental ... See more keywords
Myricetin suppresses invasion and promotes cell death in human placental choriocarcinoma cells through induction of oxidative stress.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer letters"
DOI: 10.1016/j.canlet.2017.04.014
Abstract: Myricetin is a bioactive compound found in a variety of vegetables and fruits, and its anti-cancer effects are well known. In this study, we confirmed that myricetin reduced proliferation of two choriocarcinoma cell lines (JAR… read more here.
Keywords: human placental; choriocarcinoma cells; myricetin; jar jeg ... See more keywords
Human placental cytotrophoblast epigenome dynamics over gestation and alterations in placental disease.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental cell"
DOI: 10.1016/j.devcel.2021.04.001
Abstract: The human placenta and its specialized cytotrophoblasts rapidly develop, have a compressed lifespan, govern pregnancy outcomes, and program the offspring's health. Understanding the molecular underpinnings of these behaviors informs development and disease. Profiling the extraembryonic… read more here.
Keywords: placental disease; placental cytotrophoblast; cytotrophoblast epigenome; disease ... See more keywords
Syncytins expressed in human placental trophoblast.
Sign Up to like & getrecommendations! Published in 2021 at "Placenta"
DOI: 10.1016/j.placenta.2021.01.006
Abstract: Three versions of syncytiotrophoblast exist in the human placenta: an invasive type associated with the implanting conceptus, non-invasive villous type of definitive placenta, and placental bed giant cells. Syncytins are encoded by modified env genes… read more here.
Keywords: expressed human; placental; placental trophoblast; human placental ... See more keywords
Human placental gene sets improve analysis of placental pathologies and link trophoblast and cancer invasion genes.
Sign Up to like & getrecommendations! Published in 2021 at "Placenta"
DOI: 10.1016/j.placenta.2021.06.011
Abstract: INTRODUCTION Interpretation of gene expression uses set enrichment or overrepresentation methods that depend on sets of annotated genes, such as the popular Gene Ontology. The placenta is understudied relative to other major organs creating a… read more here.
Keywords: ontology; placental pathologies; human placental; placental gene ... See more keywords
Involvement of l-type amino acid transporter 1 in the transport of gabapentin into human placental choriocarcinoma cells.
Sign Up to like & getrecommendations! Published in 2017 at "Reproductive toxicology"
DOI: 10.1016/j.reprotox.2016.11.002
Abstract: Gabapentin (GBP) is a widely used antiepileptic drug, with potential for use in the treatment of epilepsy in pregnant women. Although studies have examined GBP transport mechanisms across the blood-brain barrier, kidney, and intestine, the… read more here.
Keywords: type amino; transport; human placental; placental choriocarcinoma ... See more keywords
Congenital transmission of Mexican strains of Trypanosoma cruzi TcIa: interaction between parasite and human placental explants
Sign Up to like & getrecommendations! Published in 2021 at "Parasitology"
DOI: 10.1017/s0031182021002018
Abstract: Abstract Abstract Congenital transmission of Chagas disease plays an important role in endemic countries because it is not a diagnosis that is encountered frequently in prenatal care. Due to limited information regarding congenital transmission of… read more here.
Keywords: infection; trypanosoma cruzi; placental explants; transmission ... See more keywords
Differential Toxicity of Alkylphenols in JEG-3 Human Placental Cells: Alteration of P450 Aromatase and Cell Lipid Composition
Sign Up to like & getrecommendations! Published in 2019 at "Toxicological Sciences"
DOI: 10.1093/toxsci/kfy243
Abstract: Alkylphenols (APs) are a diverse class of chemicals that can cross the placental barrier and interfere with embryonic and fetal development. This work investigates the comparative toxicity, ability to inhibit aromatase activity, and to alter… read more here.
Keywords: toxicity; human placental; aromatase; cell ... See more keywords
Self‐assembled human placental model from trophoblast stem cells in a dynamic organ‐on‐a‐chip system
Sign Up to like & getrecommendations! Published in 2023 at "Cell Proliferation"
DOI: 10.1111/cpr.13469
Abstract: The placental barrier plays a key role in protecting the developing fetus from xenobiotics and exchanging substances between the fetus and mother. However, the trophoblast cell lines and animal models are often inadequate to recapitulate… read more here.
Keywords: placental barrier; trophoblast stem; human placental; model ... See more keywords