Assessment of chemical mixtures using biomarkers of combined biological activity: A screening study in human placentas.
Sign Up to like & getrecommendations! Published in 2021 at "Reproductive toxicology"
DOI: 10.1016/j.reprotox.2021.01.002
Abstract: Humans are simultaneously exposed to complex mixtures of chemicals with limited knowledge on potential health effects, therefore improved tools for assessing these mixtures are needed. As part of the Human Biomonitoring for Europe (HBM4EU) Project,… read more here.
Keywords: biological activity; human placentas; chemical mixtures; combined biological ... See more keywords
Bioengineering human placentas: social implications of an advancing field.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in biotechnology"
DOI: 10.1016/j.tibtech.2021.10.011
Abstract: Technological advances in bioengineering, especially in microphysiological systems and organoids, are changing the way in which placental tissue is used and perceived. These advances raise important questions surrounding consent, privacy, biobanking, and research ethics. We… read more here.
Keywords: implications advancing; social implications; placentas social; advancing field ... See more keywords
PD-L1 Expression in Human Placentas and Gestational Trophoblastic Diseases
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Gynecological Pathology"
DOI: 10.1097/pgp.0000000000000305
Abstract: One of the major immune checkpoints responsible for immune evasion in cancer cells is the interaction between programmed cell death-1 (PD-1) and its ligand (PD-L1). As human trophoblastic cells display many of the features of… read more here.
Keywords: trophoblastic diseases; trophoblastic cells; expression human; trophoblastic tumors ... See more keywords
Lacosamide effects on placental carriers of essential compounds in comparison with valproate: Studies in perfused human placentas
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia"
DOI: 10.1111/epi.17395
Abstract: Lacosamide is increasingly being prescribed to pregnant women, although its effects on the developing fetus have not been fully clarified yet. Previously, we have shown that several antiseizure medications, particularly valproate, can affect the expression… read more here.
Keywords: lacosamide effects; carriers essential; placentas lacosamide; essential compounds ... See more keywords