High‐throughput immunoaffinity enrichment and N‐glycan analysis of human plasma haptoglobin
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28280
Abstract: Haptoglobin (Hp) is a positive acute phase protein, synthesized in the liver, with four N‐glycosylation sites carrying mainly complex type N‐glycans. Its glycosylation is altered in different types of diseases but still has not been… read more here.
Keywords: high throughput; analysis; human plasma; immunoaffinity ... See more keywords
The soluble cytoplasmic tail of CD45 (ct‐CD45) in human plasma contributes to keep T cells in a quiescent state
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Immunology"
DOI: 10.1002/eji.201646405
Abstract: The cytoplasmic tail of CD45 (ct‐CD45) is proteolytically cleaved and released upon activation of human phagocytes. It acts on T cells as an inhibitory, cytokine‐like factor in vitro. Here, we show that ct‐CD45 is abundant… read more here.
Keywords: plasma; cd45 cd45; human plasma; cytoplasmic tail ... See more keywords
Multiple Epitopes of Hepatitis B Virus Surface Antigen Targeted by Human Plasma-derived Immunoglobulins Coincide with Clinically Observed Escape Mutations.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medical virology"
DOI: 10.1002/jmv.27278
Abstract: Hepatitis B Immune Globulin (HBIG) is a human plasma-derived IgG concentrate that contains a high titer of neutralizing antibodies (anti-HBs) to the hepatitis B virus (HBV) surface antigen (HBsAg). HBIG is known to be highly… read more here.
Keywords: surface antigen; human plasma; anti hbs; site ... See more keywords
Two HPLC-MS/MS methods for determination of edaravone and taurine in human plasma: Application to drug-drug interaction and pharmacokinetic studies.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of separation science"
DOI: 10.1002/jssc.201901322
Abstract: Two HPLC-MS/MS methods were developed and validated for the quantification of edaravone (method A) or taurine (method B) in human plasma. After protein precipitation, separations were achieved on an Ultimate XB-C8 (2.1 × 50 mm,… read more here.
Keywords: drug; human plasma; edaravone taurine; taurine ... See more keywords
A validated Ultra HPLC-MS/MS method for determination of TQ-B3203 in human plasma and its application to a pharmacokinetic study in Chinese patients with advanced solid tumor.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of separation science"
DOI: 10.1002/jssc.202001023
Abstract: TQ-B3203 is a new topoisomerase I inhibitor derived from camptothecin. In this paper, a simple and reliable ultra high performance liquid chromatography-tandem mass spectrometric method was developed and validated for determination of TQ-B3203 in human… read more here.
Keywords: plasma; b3203 human; human plasma; determination b3203 ... See more keywords
Sensitive and Selective Bioscreening of the Most Commonly Used Coronavirus Disease Drug, Favipiravir, and Its Co-Administered therapeutic, Meropenem, in Human Plasma.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of separation science"
DOI: 10.1002/jssc.202200332
Abstract: Favipiravir and Meropenem have been concurrently used as directly acting antiviral and antibiotic agents for the treatment of coronavirus disease in human plasma. Accurate and specific reversed phase ultra-performance liquid chromatographic and high performance thin… read more here.
Keywords: human plasma; coronavirus disease; meropenem; favipiravir ... See more keywords
Development of a capillary electrophoretic method for determination of ketorolac enantiomers in human plasma using cationic β-cyclodextrin derivative as a chiral selector.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of separation science"
DOI: 10.1002/jssc.202200601
Abstract: A novel approach for separation of ketorolac enantiomers by CE is presented. Cationic β-cyclodextrin derivative based on imidazole was synthesized and used as a chiral selector in background electrolyte. The influence of pH and ionic… read more here.
Keywords: cyclodextrin derivative; human plasma; chiral selector; ketorolac ... See more keywords
Piperine Decreases Binding of Drugs to Human Plasma and Increases Uptake by Brain Microvascular Endothelial Cells
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DOI: 10.1002/ptr.5929
Abstract: We previously reported that piperine, an active alkaloidal principal of black and long peppers, enhances drug bioavailability by inhibiting drug metabolism. Another mechanism influencing drug availability/uptake is its free fraction. Since piperine is highly lipophilic,… read more here.
Keywords: human plasma; brain microvascular; drug; piperine ... See more keywords
Isolation, Extraction and Deep-Sequencing Analysis of Extracellular RNAs (exRNAs) from Human Plasma.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1386-3_15
Abstract: Extracellular RNAs (exRNAs) are secreted by nearly all cell types and are now known to play multiple physiological roles. Human plasma, a readily available sample for biomedical analysis, was reported to contain various subpopulations of… read more here.
Keywords: analysis; human plasma; isolation extraction; extracellular rnas ... See more keywords
Isolation and Identification of Dengue Virus Interactome with Human Plasma Proteins by Affinity Purification-Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1879-0_10
Abstract: Viral proteins evolve to benefit the interaction with host proteins during the infection and replication processes. A comprehensive understanding of virus interactome with host proteins may thus lead to the identification of molecular targets for… read more here.
Keywords: virus interactome; dengue virus; human plasma; plasma proteins ... See more keywords
In-Depth, Reproducible Analysis of Human Plasma Using IgY 14 and SuperMix Immunodepletion.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7057-5_7
Abstract: Identification of cancer and other disease biomarkers in human plasma has been exceptionally challenging due to the complex nature of plasma and the presence of a moderate number of high- and medium-abundance proteins which mask… read more here.
Keywords: depth; plasma; igy supermix; human plasma ... See more keywords