Comprehensive phenotyping of human platelets by single‐cell cytometry
Sign Up to like & getrecommendations! Published in 2022 at "Cytometry Part A"
DOI: 10.1002/cyto.a.24531
Abstract: Platelets are small anucleate blood cells that contribute to hemostasis, immunity, and inflammation. Circulating platelets are heterogeneous in size, age, receptor expression, and reactivity. They inherit many features from megakaryocytes and are further modified on… read more here.
Keywords: cell; human platelets; phenotyping human; single cell ... See more keywords
Morphofunctional Properties of Human Platelets Treated with Silver Nanoparticles
Sign Up to like & getrecommendations! Published in 2017 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-017-3966-9
Abstract: We studied structural and functional properties of human platelets in the presence of nanosilver particles. Incubation with 0.05-5 μM silver nanoparticles suppressed platelet adhesion in a dose-dependent manner without affecting internal platelet structure; during adhesion,… read more here.
Keywords: human platelets; silver nanoparticles; morphofunctional properties; platelet ... See more keywords
Ultralow fouling of fibrinogen and human platelets on ulvan multilayer-coated solid surfaces
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Industrial and Engineering Chemistry"
DOI: 10.1016/j.jiec.2019.10.017
Abstract: Abstract Enhancement of blood compatibility with the implant surface is critical for biomedical devices. Coating solid surfaces with an anticoagulant is a potentially promising strategy to improve blood compatibility with the implant surface. This study… read more here.
Keywords: human platelets; blood compatibility; ulvan multilayer; solid surfaces ... See more keywords
Defining the TLT-1 interactome from resting and activated human platelets.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2020.103638
Abstract: The triggering receptor expressed on myeloid cells (TREM) protein family forms a class of type I transmembrane proteins expressed in immune cells that play important roles in innate and adaptive immune responses. The TREM family… read more here.
Keywords: interactome resting; human platelets; tlt; tlt interactome ... See more keywords
Human platelets display dysregulated sepsis-associated autophagy, induced by altered LC3 protein-protein interaction of the Vici-protein EPG5.
Sign Up to like & getrecommendations! Published in 2021 at "Autophagy"
DOI: 10.1080/15548627.2021.1990669
Abstract: Platelets mediate central aspects of host responses during sepsis, an acute profoundly systemic inflammatory response due to infection. Macroautophagy/autophagy, which mediates critical aspects of cellular responses during inflammatory conditions, is known to be a functional… read more here.
Keywords: sepsis; vici; human platelets; protein protein ... See more keywords
P3502Transmission electron microscopy reveals ultrastructural differences between reticulated and non-reticulated human platelets
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz745.0367
Abstract: Reticulated platelets (RP) are the youngest circulating platelets in blood. Compared to older platelets, RP represent a highly active prothrombotic platelet population associated with an increased risk for cardiovascular events, mortality and impaired response to… read more here.
Keywords: human platelets; microscopy reveals; microscopy; dense granules ... See more keywords
Direct Impact of Human Platelets on the Development of Transplant Arteriosclerosis.
Sign Up to like & getrecommendations! Published in 2021 at "Transplantation"
DOI: 10.1097/tp.0000000000003935
Abstract: BACKGROUND Platelets play an important role in the pathogenesis of inflammatory and proliferative vascular changes. The aim of this study was to investigate whether human platelets are able to induce transplant arteriosclerosis in a humanized… read more here.
Keywords: human platelets; transplant arteriosclerosis; development transplant; activated human ... See more keywords
Functional links between Disabled‐2 Ser723 phosphorylation and thrombin signaling in human platelets
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.13785
Abstract: Essentials Disabled‐2 (Dab2) phosphorylation status in thrombin signaling of human platelet was investigated. Ser723 was the major Dab2 phosphorylation site in human platelets stimulated by thrombin. Dab2 S723 phosphorylation (pS723) caused the dissociation of Dab2‐CIN85… read more here.
Keywords: human platelets; phosphorylation; dab2; signaling human ... See more keywords
Human platelets labeled at two discrete biotin densities are functional in vitro and are detected in vivo in the murine circulation: A promising approach to monitor platelet survival in vivo in clinical research
Sign Up to like & getrecommendations! Published in 2021 at "Transfusion"
DOI: 10.1111/trf.16312
Abstract: The production of platelet concentrates (PCs) is evolving, and their survival capacity needs in vivo evaluation. This requires that the transfused platelets (PLTs) be distinguished from those of the recipient. Labeling at various biotin (Bio)… read more here.
Keywords: human platelets; two discrete; labeled two; platelets labeled ... See more keywords
Role of a novel MCU variant in Ca2+ handling in human platelets
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5733260
Abstract: Introduction: Discovery of the molecular identity of the mitochondrial Ca2+ (mtCa2+) uniporter complex (mtCUC) provides rapid progress in characterizing mtCa2+ handling and its roles in regulating cellular functions. MCU, a pore-forming subunit of mtCUC, which… read more here.
Keywords: mcu; cell; human platelets; mcu variant ... See more keywords
Rac Regulates the TRAP-Induced Release of Phosphorylated-HSP27 from Human Platelets via p38 MAP Kinase but Not JNK
Sign Up to like & getrecommendations! Published in 2018 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000493456
Abstract: Background/Aims: Thrombin induces the activation of human platelets through protease-activated receptor (PAR) 1 and PAR4, and Rac, a member of the Rho family of small GTPases, is implicated in PAR activation. We previously reported that… read more here.
Keywords: human platelets; p38; phosphorylated hsp27; release phosphorylated ... See more keywords