Hyperglycemia alters mitochondrial respiration efficiency and mitophagy in human podocytes.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2021.112758
Abstract: Podocytes constitute the outer layer of the renal glomerular filtration barrier. Their energy requirements strongly depend on efficient oxidative respiration, which is tightly connected with mitochondrial dynamics. We hypothesized that hyperglycemia modulates energy metabolism in… read more here.
Keywords: mitochondrial respiration; respiration; hyperglycemia alters; hyperglycemia ... See more keywords
Identification of ARMH4 and WIPF3 as human podocyte proteins with potential roles in immunomodulation and cytoskeletal dynamics
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0280270
Abstract: The podocyte is a specialized cell type critically involved in maintaining the selective filtration barrier of the kidney. Podocytes are primary or secondary targets for a multitude of kidney diseases. Despite intense investigation, the transcriptome… read more here.
Keywords: podocyte; human kidneys; overexpression; armh4 wipf3 ... See more keywords