Water turnover among human populations: Effects of environment and lifestyle
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DOI: 10.1002/ajhb.23365
Abstract: To discuss the environmental and lifestyle determinants of water balance in humans and identify the gaps in current research regarding water use across populations. Methods: We investigated intraspecific variation in water turnover by comparing data… read more here.
Keywords: human populations; among human; water; turnover among ... See more keywords
Ancestral reconstruction and correlation of the frequencies of the hemoglobin S allele and the Duffy blood group alleles in human populations
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Human Biology"
DOI: 10.1002/ajhb.23832
Abstract: Objectives: Malaria is an important selective force for human genetic adaptation due to the sustained, lethal impact it has had on populations worldwide. High frequencies of both hemoglobin S and the null allele FYBES of… read more here.
Keywords: duffy blood; human populations; ancestral reconstruction; correlation frequencies ... See more keywords
The road less traveled: from genotype to phenotype in flies and humans
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DOI: 10.1007/s00335-017-9722-7
Abstract: Understanding how genomic variation gives rise to phenotypic variation is essential for elucidating mechanisms of adaptive evolution, plant and animal breeding, and precision medicine. However, identifying causal links between DNA sequence variants and variation in… read more here.
Keywords: human populations; variation; less traveled; genetic architectures ... See more keywords
Evolutionary and population (epi)genetics of immunity to infection
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DOI: 10.1007/s00439-020-02167-x
Abstract: Immune response is one of the functions that have been more strongly targeted by natural selection during human evolution. The evolutionary genetic dissection of the immune system has greatly helped to distinguish genes and functions… read more here.
Keywords: human populations; genetics; evolutionary population; immune system ... See more keywords
Dietary patterns in human populations from northwest Patagonia during Holocene: an approach using Binford’s frames of reference and Bayesian isotope mixing models
Sign Up to like & getrecommendations! Published in 2017 at "Archaeological and Anthropological Sciences"
DOI: 10.1007/s12520-016-0459-0
Abstract: The goal of this paper is to assess the variation in the proportional contribution of diverse resources to the diet of human populations from northwest Patagonia (Argentina) throughout the Middle-Late Holocene. Particularly, we assessed the… read more here.
Keywords: human populations; holocene; binford frames; northwest patagonia ... See more keywords
The genomic signatures of natural selection in admixed human populations.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2022.02.011
Abstract: Admixture has been a pervasive phenomenon in human history, extensively shaping the patterns of population genetic diversity. There is increasing evidence to suggest that admixture can also facilitate genetic adaptation to local environments, i.e., admixed… read more here.
Keywords: adaptive admixture; human populations; admixture; selection admixed ... See more keywords
GM biofortified crops: potential effects on targeting the micronutrient intake gap in human populations.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2017.02.003
Abstract: Genetic engineering has been successfully applied to increase micronutrient content in staple crops. Nutrition evidence is key to ensure scale-up and successful implementation. Unlike conventional plant breeding efforts, research on the efficacy or effectiveness of… read more here.
Keywords: human populations; gap; intake; biofortified crops ... See more keywords
The analysis of GSTA1 promoter genetic and functional diversity of human populations
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DOI: 10.1038/s41598-021-83996-2
Abstract: GSTA1 encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. GSTA1 has several functional SNPs within… read more here.
Keywords: human populations; gsta1 promoter; analysis; promoter haplotypes ... See more keywords
The Impact of Modern Admixture on Archaic Human Ancestry in Human Populations
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DOI: 10.1093/gbe/evad066
Abstract: Abstract Admixture, the genetic merging of parental populations resulting in mixed ancestry, has occurred frequently throughout the course of human history. Numerous admixture events have occurred between human populations across the world, which have shaped… read more here.
Keywords: recent admixture; admixture; ancestry; human populations ... See more keywords
Cultural sexual selection in monogamous human populations
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DOI: 10.1098/rsos.160946
Abstract: In humans, both sexes sometimes show peculiar mating preferences that do not appear to increase their fitness either directly or indirectly. As humans may transmit their preferences and target culturally, and these may be artificially… read more here.
Keywords: preference trait; human populations; selection monogamous; sexual selection ... See more keywords
In silico design of a Zika virus non-structural protein 5 aiming vaccine protection against zika and dengue in different human populations
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biomedical Science"
DOI: 10.1186/s12929-017-0395-z
Abstract: BackgroundThe arboviruses Zika virus (ZIKV) and Dengue virus (DENV) have important epidemiological impact in Brazil and other tropical regions of the world. Recently, it was shown that previous humoral immunity to DENV enhances ZIKV replication… read more here.
Keywords: protein; human populations; denv; zika virus ... See more keywords