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Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2020.108670
Abstract: Inflammation-dependent base deaminases promote therapeutic resistance in many malignancies. However, their roles in human pre-leukemia stem cell (pre-LSC) evolution to acute myeloid leukemia stem cells (LSCs) had not been elucidated. Comparative whole-genome and whole-transcriptome sequencing…
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Keywords:
evolution;
human pre;
stem;
pre lsc ... See more keywords
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Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-018-08244-0
Abstract: Human pre-implantation embryonic development involves extensive changes in chromatin structure and transcriptional activity. Here, we report on LiCAT-seq, a technique that enables simultaneous profiling of chromatin accessibility and gene expression with ultra-low input of cells,…
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Keywords:
pre implantation;
accessibility transcriptome;
accessibility;
human pre ... See more keywords
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Published in 2024 at "Communications Biology"
DOI: 10.1038/s42003-025-08497-8
Abstract: The functional role of visual activations of human pre-frontal cortex remains a deeply debated question. Its significance extends to fundamental issues of functional localization and global theories of consciousness. Here we addressed this question by…
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Keywords:
text related;
functionality dynamics;
related functionality;
pre frontal ... See more keywords
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Published in 2025 at "Human reproduction update"
DOI: 10.1093/humupd/dmaf022
Abstract: BACKGROUND Infertility is a growing global challenge, with ARTs significantly improving birth rates for infertile couples. However, ART conceptions are associated with a higher risk of negative obstetrical and perinatal outcomes, with potential long-term effects…
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Keywords:
pre implantation;
culture;
implantation;
gene ... See more keywords