Non-human primate models of PD to test novel therapies
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neural Transmission"
DOI: 10.1007/s00702-017-1722-y
Abstract: Non-human primate (NHP) models of Parkinson disease show many similarities with the human disease. They are very useful to test novel pharmacotherapies as reviewed here. The various NHP models of this disease are described with… read more here.
Keywords: human primate; non human; test novel; nhp models ... See more keywords
Climate change impacts on potential future ranges of non-human primate species
Sign Up to like & getrecommendations! Published in 2020 at "Climatic Change"
DOI: 10.1007/s10584-020-02776-5
Abstract: Climate change is likely to negatively affect the habitats of non-human primate species. Recent research has identified a near-linear relationship between cumulative CO 2 emissions, and the resulting regional and seasonal temperature increase. Here, we… read more here.
Keywords: human primate; non human; primate; climate change ... See more keywords
A non-human primate model for stable chronic Parkinson’s disease induced by MPTP administration based on individual behavioral quantification
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroscience Methods"
DOI: 10.1016/j.jneumeth.2018.10.037
Abstract: BACKGROUND The guidelines for applying individual adjustments to macaques according to the severity of behavioral symptoms during 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment were provided to reproduce stable chronic Parkinsonism in a recent study (Potts et al., 2014).… read more here.
Keywords: human primate; administration; administration based; non human ... See more keywords
Head mounted telemetry system for seizures monitoring and sleep scoring on non-human primate
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroscience Methods"
DOI: 10.1016/j.jneumeth.2020.108915
Abstract: Radio telemetry systems are a useful way to continuously monitor broad electrical neuronal activity in behaving animals. It can also be used to study sleep disturbances or monitor seizure activity. Many different telemeter styles are… read more here.
Keywords: human primate; non human; system; seizures monitoring ... See more keywords
Non-human primate models of human respiratory infections
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Immunology"
DOI: 10.1016/j.molimm.2021.04.010
Abstract: Respiratory pathogens represent a great burden for humanity and a potential source of new pandemics, as illustrated by the recent emergence of coronavirus disease 2019 (COVID-19). In recent decades, biotechnological advances have led to the… read more here.
Keywords: respiratory infections; human primate; primate models; non human ... See more keywords
An Open Resource for Non-human Primate Imaging
Sign Up to like & getrecommendations! Published in 2018 at "Neuron"
DOI: 10.1016/j.neuron.2018.08.039
Abstract: Summary Non-human primate neuroimaging is a rapidly growing area of research that promises to transform and scale translational and cross-species comparative neuroscience. Unfortunately, the technological and methodological advances of the past two decades have outpaced… read more here.
Keywords: human primate; resource non; non human; open resource ... See more keywords
SRT1720 Pretreatment Promotes Mitochondrial Biogenesis of Aged Human Mesenchymal Stem Cells and Improves Their Engraftment in Post-infarct Non-Human Primate Hearts.
Sign Up to like & getrecommendations! Published in 2021 at "Stem cells and development"
DOI: 10.1089/scd.2020.0149
Abstract: Declined function of aged mesenchymal stem cells (MSCs) diminishes the benefits of cell therapy for myocardial infarction (MI). Our previous study has demonstrated that SRT1720, a specific SIRT1 activator, could protect aged human MSCs (hMSCs)… read more here.
Keywords: human primate; stem cells; non human; aged hmscs ... See more keywords
Revisiting 35 and 94 GHZ Millimeter Wave Exposure to the Non-human Primate Eye.
Sign Up to like & getrecommendations! Published in 2020 at "Health Physics"
DOI: 10.1097/hp.0000000000001216
Abstract: A previous study reported thermal effects resulting from millimeter wave exposures at 35 and 94 GHz on non-human primates, specifically rhesus monkeys' (Macaca mulatta) corneas, but the data exhibited large variations in the observed temperatures… read more here.
Keywords: millimeter wave; human primate; non human; eye ... See more keywords
Transmission models indicate Ebola virus persistence in non-human primate populations is unlikely
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Royal Society Interface"
DOI: 10.1098/rsif.2021.0638
Abstract: Infectious diseases that kill their hosts may persist locally only if transmission is appropriately balanced by susceptible recruitment. Great apes die of Ebola virus disease (EVD) and have transmitted ebolaviruses to people. However, understanding the… read more here.
Keywords: transmission; ebola virus; transmission models; non human ... See more keywords
Transplantation of insulin-producing cells derived from human MSCs to treat diabetes in a non-human primate model.
Sign Up to like & getrecommendations! Published in 2023 at "Artificial organs"
DOI: 10.1111/aor.14538
Abstract: BACKGROUND Islet cell transplantation is an emerging therapy in the treatment of diabetes mellitus. Differentiation of islet cells from mesenchymal stem cells (MSCs) is a potential solution to the challenge of insufficient donor sources. This… read more here.
Keywords: human primate; ipcs; transplantation; insulin ... See more keywords
The non‐human primate kidney transcriptome in fetal development
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Medical Primatology"
DOI: 10.1111/jmp.12340
Abstract: Little is known about the repertoire of non‐human primate kidney genes expressed throughout development. The present work establishes an understanding of the primate renal transcriptome during fetal development in the context of renal maturation. read more here.
Keywords: human primate; transcriptome fetal; non human; fetal development ... See more keywords