Ethyl acetate fraction from methanol extraction of Vitis thunbergii var. taiwaniana induced G0/G1 phase arrest via inhibition of cyclins D and E and induction of apoptosis through caspase‐dependent and ‐independent pathways in human prostate carcinoma DU145 cells
Sign Up to like & getrecommendations! Published in 2018 at "Environmental Toxicology"
DOI: 10.1002/tox.22491
Abstract: Vitis thunbergii var. taiwaniana (VTT) is a wild grape native to Taiwan, belonging to the Vitaceae family and Vitis genus, and widely used as folk herbal medicine. It is traditionally used for the treatment of… read more here.
Keywords: human prostate; apoptosis; du145 cells; du145 ... See more keywords
The bispecific anti-CD3 × anti-CD155 antibody mediates T cell immunotherapy for human prostate cancer
Sign Up to like & getrecommendations! Published in 2018 at "Investigational New Drugs"
DOI: 10.1007/s10637-018-0683-9
Abstract: SummaryExpression of CD155 differs between tumor and normal tissues, and high expression of this molecule can promote tumor metastasis. Here, we investigate whether CD155 can serve as a target for T cell-mediated immunotherapy of human… read more here.
Keywords: cd155; human prostate; prostate cancer; anti ... See more keywords
Could Cisplatin Loading on Biosynthesized Silver Nanoparticles Improve Its Therapeutic Efficacy on Human Prostate Cancer Cell Line and Reduce Its In Vivo Nephrotoxic Effects?
Sign Up to like & getrecommendations! Published in 2021 at "Biological trace element research"
DOI: 10.1007/s12011-021-02677-3
Abstract: Nanotechnology is a possible solution to the drawbacks of cancer therapy because it decreases the clinical side effects of chemotherapeutic drugs and increases their clinical activity. Thus, this work compared the in vitro cytotoxic activity… read more here.
Keywords: silver nanoparticles; human prostate; prostate cancer; cancer ... See more keywords
CTHRC1 affects malignant tumor cell behavior and is regulated by miR-30e-5p in human prostate cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.02.098
Abstract: Collagen Triple Helix Repeat Containing 1 (CTHRC1) has been picked out as a cancer-related, secreted glycoprotein that possesses multifaceted functions such as wound repair, the formation of adipose tissue, hepatocytes fibrosis, and bone remodeling. This… read more here.
Keywords: human prostate; cthrc1; mir 30e; prostate cancer ... See more keywords
Significantly altered expression of miR-511-3p and its target AKT3 has negative prognostic value in human prostate cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Biochimie"
DOI: 10.1016/j.biochi.2017.06.007
Abstract: PURPOSE In this study, we assessed the expression and functions of microRNA-511-3p (miR-511-3p) in human prostate cancer (CaP). METHODS Gene expressions of miR-511-3p in CaP cells and human CaP tumors were assessed by qPCR. In… read more here.
Keywords: human prostate; target; mir 511; cancer ... See more keywords
Procyanidin from peanut skin induces antiproliferative effect in human prostate carcinoma cells DU145.
Sign Up to like & getrecommendations! Published in 2018 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2018.04.008
Abstract: In this study, the antiproliferative activity of peanut skin procyanidins (PSP) and six fractions (PSP-1∼6) isolated from PSP by several chromatographic steps on the human prostate cancer DU145 cells were evaluated. The results showed that PSP… read more here.
Keywords: prostate; procyanidin peanut; human prostate; du145 cells ... See more keywords
DESNT: A Poor Prognosis Category of Human Prostate Cancer.
Sign Up to like & getrecommendations! Published in 2018 at "European urology focus"
DOI: 10.1016/j.euf.2017.01.016
Abstract: BACKGROUND A critical problem in the clinical management of prostate cancer is that it is highly heterogeneous. Accurate prediction of individual cancer behaviour is therefore not achievable at the time of diagnosis leading to substantial… read more here.
Keywords: poor prognosis; human prostate; prognosis category; prostate cancer ... See more keywords
Liposomal Binuclear Ir(III)–Cu(II) Coordination Compounds with Phosphino-Fluoroquinolone Conjugates for Human Prostate Carcinoma Treatment
Sign Up to like & getrecommendations! Published in 2022 at "Inorganic Chemistry"
DOI: 10.1021/acs.inorgchem.2c03015
Abstract: Novel heteronuclear IrIII–CuII coordination compounds ([Ir(η5-Cp*)Cl2Pcfx-Cu(phen)](NO3)·1.75(CH3OH)·0.75(H2O) (1), [Ir(η5-Cp*)Cl2Pnfx-Cu(phen)](NO3)·1.75(CH3OH)·0.75(H2O) (2), [Ir(η5-Cp*)Cl2Plfx-Cu(phen)](NO3)·1.3(H2O)·1.95(CH3OH) (3), [Ir(η5-Cp*)Cl2Psfx-Cu(phen)] (4)) bearing phosphines derived from fluoroquinolones, namely, sparfloxacin (Hsfx), ciprofloxacin (Hcfx), lomefloxacin (Hlfx), and norfloxacin (Hnfx), have been synthesized and studied as possible… read more here.
Keywords: coordination compounds; coordination; phen; geometry ... See more keywords
The Kunitz Domain I of Hepatocyte Growth Factor Activator Inhibitor-2 Inhibits Matriptase Activity and Invasive Ability of Human Prostate Cancer Cells
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DOI: 10.1038/s41598-017-15415-4
Abstract: Dysregulation of pericellular proteolysis is often required for tumor invasion and cancer progression. It has been shown that down-regulation of hepatocyte growth factor activator inhibitor-2 (HAI-2) results in activation of matriptase (a membrane-anchored serine protease),… read more here.
Keywords: human prostate; prostate cancer; matriptase; hai ... See more keywords
Carbon sources and pathways for citrate secreted by human prostate cancer cells determined by NMR tracing and metabolic modeling
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2024357119
Abstract: Significance The human prostate accumulates high luminal citrate levels to serve sperm viability. There is only indirect qualitative evidence about metabolic pathways and carbon sources maintaining these levels. Human citrate-secreting prostate cancer cells were supplied… read more here.
Keywords: prostate cancer; carbon; citrate; carbon sources ... See more keywords
Capacitive hyperthermia as an alternative to brachytherapy in DNA damages of human prostate cancer cell line (DU-145)
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Radiation Biology"
DOI: 10.1080/09553002.2019.1532608
Abstract: Abstract Purpose: The aim of this study was the evaluation of induced DNA damages of human prostate cancer cells, DU-145, treated with a combination of radiofrequency capacitive hyperthermia (HT) and teletherapy (EBRT) compared to a… read more here.
Keywords: human prostate; ebrt; prostate cancer; damages human ... See more keywords