Bisphenol A Exposure Changes the Transcriptomic and Proteomic Dynamics of Human Retinoblastoma Y79 Cells
Sign Up to like & getrecommendations! Published in 2021 at "Genes"
DOI: 10.3390/genes12020264
Abstract: Bisphenol A (BPA) is a xenoestrogen chemical commonly used to manufacture polycarbonate plastics and epoxy resin and might affect various human organs. However, the cellular effects of BPA on the eyes have not been widely… read more here.
Keywords: y79 cells; bpa; bisphenol exposure; exposure ... See more keywords
microRNA-497 overexpression decreases proliferation, migration and invasion of human retinoblastoma cells via targeting vascular endothelial growth factor A.
Sign Up to like & getrecommendations! Published in 2017 at "Oncology letters"
DOI: 10.3892/ol.2017.6083
Abstract: The expression level and roles of microRNA-497 (miR-497) have been frequently reported in previous studies on cancer. However, its expression, function and associated molecular mechanisms in retinoblastoma remain unknown. In the present study, miR-497 expression… read more here.
Keywords: invasion; mir 497; retinoblastoma; migration ... See more keywords
Inhibitory effect of carboplatin in combination with bevacizumab on human retinoblastoma in an in vitro and in vivo model
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DOI: 10.3892/ol.2017.6827
Abstract: Retinoblastoma is the most common type of malignant intraocular tumor in children, and angiogenesis is required for tumor growth and expansion. The present study investigated whether use of the vascular endothelial growth factor inhibitor antibody… read more here.
Keywords: combination; vitro vivo; retinoblastoma; carboplatin ... See more keywords
Corosolic acid induces cell cycle arrest and cell apoptosis in human retinoblastoma Y-79 cells via disruption of MELK-FoxM1 signaling.
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DOI: 10.3892/or.2018.6339
Abstract: Retinoblastoma (Rb) is the most frequent primary intraocular tumor usually diagnosed in infants and children, and current therapy for such disease is still limited. Corosolic acid (CA), an ursane-type pentacyclic triterpene, has been assessed as a promising… read more here.
Keywords: cell cycle; retinoblastoma; melk foxm1; human retinoblastoma ... See more keywords