Glycan recognition in globally dominant human rotaviruses
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DOI: 10.1038/s41467-018-05098-4
Abstract: Rotaviruses (RVs) cause life-threatening diarrhea in infants and children worldwide. Recent biochemical and epidemiological studies underscore the importance of histo-blood group antigens (HBGA) as both cell attachment and susceptibility factors for the globally dominant P[4],… read more here.
Keywords: recognition globally; human rotaviruses; globally dominant; glycan recognition ... See more keywords
Isolation, Propagation and Genotyping of Human Rotaviruses Circulating among Children with Gastroenteritis in Two Egyptian University Hospitals
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DOI: 10.3390/biology11101413
Abstract: Simple Summary Group A rotaviruses are the most common cause of acute gastroenteritis affecting Egyptian children under the age of five, with symptoms ranging from asymptomatic infection to severe dehydration or death. In the present… read more here.
Keywords: human rotaviruses; circulating among; cell; rotaviruses circulating ... See more keywords
Human Rotaviruses of Multiple Genotypes Acquire Conserved VP4 Mutations during Serial Passage
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DOI: 10.3390/v16060978
Abstract: Human rotaviruses exhibit limited tropism and replicate poorly in most cell lines. Attachment protein VP4 is a key rotavirus tropism determinant. Previous studies in which human rotaviruses were adapted to cultured cells identified mutations in… read more here.
Keywords: human rotaviruses; five genotypes; rotavirus; passage ... See more keywords