A model of metformin mitochondrial metabolism in metachromatic leukodystrophy: first description of human Schwann cells transfected with CRISPR-Cas9
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DOI: 10.1098/rsob.210371
Abstract: Metachromatic leukodystrophy is a neurological lysosomal deposit disease that affects public health despite its low incidence in the population. Currently, few reports are available on pathophysiological events related to enzyme deficiencies and subsequent sulfatide accumulation.… read more here.
Keywords: human schwann; crispr cas9; schwann cells; metachromatic leukodystrophy ... See more keywords
Culture Conditions for Human Induced Pluripotent Stem Cell-Derived Schwann Cells: A Two-Centre Study
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DOI: 10.3390/ijms24065366
Abstract: Adult human Schwann cells represent a relevant tool for studying peripheral neuropathies and developing regenerative therapies to treat nerve damage. Primary adult human Schwann cells are, however, difficult to obtain and challenging to propagate in… read more here.
Keywords: human schwann; cell; schwann cells; schwann ... See more keywords