Structural basis for selective inhibition of human serine hydroxymethyltransferase by secondary bile acid conjugate
Sign Up to like & getrecommendations! Published in 2021 at "iScience"
DOI: 10.1016/j.isci.2021.102036
Abstract: Summary Bile acids are metabolites of cholesterol that facilitate lipid digestion and absorption in the small bowel. Bile acids work as agonists of receptors to regulate their own metabolism. Bile acids also regulate other biological… read more here.
Keywords: bile; bile acids; human serine; secondary bile ... See more keywords
The Energy Landscape of Human Serine Racemase
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DOI: 10.3389/fmolb.2018.00112
Abstract: Human serine racemase is a pyridoxal 5′-phosphate (PLP)-dependent dimeric enzyme that catalyzes the reversible racemization of L-serine and D-serine and their dehydration to pyruvate and ammonia. As D-serine is the co-agonist of the N-methyl-D-aspartate receptors… read more here.
Keywords: human serine; energy landscape; serine racemase; racemase ... See more keywords