Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors
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DOI: 10.1016/j.cell.2019.10.010
Abstract: Summary The peptidergic system is the most abundant network of ligand-receptor-mediated signaling in humans. However, the physiological roles remain elusive for numerous peptides and more than 100 G protein-coupled receptors (GPCRs). Here we report the… read more here.
Keywords: human signaling; discovery human; protein coupled; coupled receptors ... See more keywords
The Pathogenesis of Atherosclerosis Based on Human Signaling Networks and Stem Cell Expression Data
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DOI: 10.7150/ijbs.27896
Abstract: Atherosclerosis is a common and complex disease, whose morbidity increased significantly. Here, an integrated approach was proposed to elucidate systematically the pathogenesis of atherosclerosis from a systems biology point of view. Two weighted human signaling… read more here.
Keywords: human signaling; signaling networks; expression; pathogenesis atherosclerosis ... See more keywords