pH-dependent structural modulation is conserved in the human small heat shock protein HSBP1
Sign Up to like & getrecommendations! Published in 2017 at "Cell Stress and Chaperones"
DOI: 10.1007/s12192-017-0783-z
Abstract: The holdase activity and oligomeric propensity of human small heat shock proteins (sHSPs) are regulated by environmental factors. However, atomic-level details are lacking for the mechanisms by which stressors alter sHSP responses. We previously demonstrated… read more here.
Keywords: dependent structural; heat shock; small heat; human small ... See more keywords
Establishment and characterization of an in vitro human small airway model (SmallAir™)
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2016.12.006
Abstract: Graphical abstract Figure. No caption available. ABSTRACT We report here the establishment and characterization of an in vitro human small airway model (SmallAir™). The epithelial cells were isolated from the distal lungs by enzymatic digestion.… read more here.
Keywords: vitro human; human small; model; establishment characterization ... See more keywords
Shared expression of mucin12 in Ascaris lumbricoides and the human small intestine.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and biochemical parasitology"
DOI: 10.1016/j.molbiopara.2018.11.004
Abstract: This study focuses on the host-parasite relationship of human Ascaris lumbricoides, which is a parasite of the small intestine and is also one of the commonest parasites worldwide. As part of this investigation, we examined… read more here.
Keywords: lumbricoides human; human small; ascaris lumbricoides; small intestine ... See more keywords
Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-21201-7
Abstract: Here we describe a method for fabricating a primary human Small Intestine-on-a-Chip (Intestine Chip) containing epithelial cells isolated from healthy regions of intestinal biopsies. The primary epithelial cells are expanded as 3D organoids, dissociated, and… read more here.
Keywords: human small; intestine chip; small intestine; primary human ... See more keywords
O-081 High variability of molecular isoforms of AMH in follicular fluid and granulosa cells from human small antral follicles
Sign Up to like & getrecommendations! Published in 2021 at "Human Reproduction"
DOI: 10.1093/humrep/deab125.011
Abstract: Is the composition of AMH isoforms different in follicular fluids (FF) and granulosa cells (GCs) from human small antral follicles? There is a high viability of AMH isoforms in FFs and GCs. Even between same… read more here.
Keywords: granulosa cells; human small; small antral; antral follicles ... See more keywords
Downregulation of USP32 inhibits cell proliferation, migration and invasion in human small cell lung cancer
Sign Up to like & getrecommendations! Published in 2017 at "Cell Proliferation"
DOI: 10.1111/cpr.12343
Abstract: Ubiquitin specific protease 32 (USP32) is a highly conserved but uncharacterized gene, which has been reported to be associated with growth of breast cancer cells. However, the role of USP32 in human small cell lung… read more here.
Keywords: human small; cell lung; lung cancer; cancer ... See more keywords
Ontogeny and Biology of Human Small Airway Epithelial Club Cells
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Respiratory and Critical Care Medicine"
DOI: 10.1164/rccm.201710-2107oc
Abstract: Rationale: Little is known about human club cells, dome‐shaped cells with dense cytoplasmic granules and microvilli that represent the major secretory cells of the human small airways (at least sixth‐generation bronchi). Objectives: To define the… read more here.
Keywords: club; club cells; human small; small airway ... See more keywords
Cell-specific expression of lung disease risk-related genes in the human small airway epithelium
Sign Up to like & getrecommendations! Published in 2020 at "Respiratory Research"
DOI: 10.1186/s12931-020-01442-9
Abstract: Background The human small airway epithelium (SAE) plays a central role in the early events in the pathogenesis of most inherited and acquired lung disorders. Little is known about the molecular phenotypes of the specific… read more here.
Keywords: risk; human small; disease; small airway ... See more keywords
Asymmetric mucosal structure, mesenteric versus antimesenteric, in mouse, rat, and human small intestines
Sign Up to like & getrecommendations! Published in 2022 at "Physiological Reports"
DOI: 10.14814/phy2.15547
Abstract: The morphology of the small intestinal mucosa is reflected by the degree of stimuli. Previous studies have come to different conclusion about whether the mucosa is equally symmetrical. The aim of the study is to… read more here.
Keywords: structure; versus antimesenteric; mesenteric versus; human small ... See more keywords
Insights on Human Small Heat Shock Proteins and Their Alterations in Diseases
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.842149
Abstract: The family of the human small Heat Shock Proteins (HSPBs) consists of ten members of chaperones (HSPB1-HSPB10), characterized by a low molecular weight and capable of dimerization and oligomerization forming large homo- or hetero-complexes. All… read more here.
Keywords: shock proteins; small heat; heat shock; human small ... See more keywords
Hydroxysafflor Yellow A Suppresses Platelet Activating Factor-Induced Activation of Human Small Airway Epithelial Cells
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2018.00859
Abstract: Hydroxysafflor yellow A (HSYA) is a chemical component isolated from the Chinese medicine Carthamus tinctorius L. HSYA has numerous pharmacological effects, including protecting against and mitigating some respiratory diseases such as acute lung injury and… read more here.
Keywords: platelet activating; human small; activating factor; hydroxysafflor yellow ... See more keywords