Iberiotoxin and clofilium regulate hyperactivation, acrosome reaction, and ion homeostasis synergistically during human sperm capacitation
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23671
Abstract: Potassium channels play essential roles in the regulation of male fertility. However, potassium channels mediating K+ currents in human sperm (IKSper) remain controversial. Besides SLO3, the SLO1 potassium channel is a potential candidate for human… read more here.
Keywords: capacitation; hyperactivation; clofilium; acrosome reaction ... See more keywords
DNA damage in human sperm: The sperm chromosome assay
Sign Up to like & getrecommendations! Published in 2022 at "Reproductive Medicine and Biology"
DOI: 10.1002/rmb2.12461
Abstract: Sperm DNA damage is a major cause of pre‐ and post‐implantation embryonic loss in humans. However, the factors that control how and when such DNA damage occurs in human sperm are poorly understood. read more here.
Keywords: damage; damage human; dna damage; sperm sperm ... See more keywords
Obesity significantly alters the human sperm proteome, with potential implications for fertility
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-020-01707-8
Abstract: Purpose In men, obesity may lead to poor semen parameters and reduced fertility. However, the causative links between obesity and male infertility are not totally clear, particularly on a molecular level. As such, we investigated… read more here.
Keywords: human sperm; implications fertility; sperm proteome; obese men ... See more keywords
Protective Effects of Curcumin on the Outcome of Cryopreservation in Human Sperm
Sign Up to like & getrecommendations! Published in 2021 at "Reproductive Sciences"
DOI: 10.1007/s43032-021-00572-9
Abstract: Cryopreservation causes decreased sperm fertility potential due to reactive oxygen species (ROS) production and physical-chemical damage, resulting in reduced sperm viability and motility. The addition of antioxidants to freezing media could protect sperm from cryo-damage,… read more here.
Keywords: human sperm; effects curcumin; cryopreservation; damage ... See more keywords
Human Sperm Rotation is Regulated by Asymmetrically Positioned Flagellar Control Units
Sign Up to like & getrecommendations! Published in 2018 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2017.11.1719
Abstract: Author(s): Mannowetz, Nadja; Miller, Melissa R; Kenny, Samuel J; Mansell, Steven A; Wojcik, Michal; Zucker, Robert S; Xu, Ke; Lishko, Polina V read more here.
Keywords: regulated asymmetrically; human sperm; sperm rotation; asymmetrically positioned ... See more keywords
A novel deep learning method for automatic assessment of human sperm images
Sign Up to like & getrecommendations! Published in 2019 at "Computers in biology and medicine"
DOI: 10.1016/j.compbiomed.2019.04.030
Abstract: Sperm morphology analysis (SMA) is a very important factor in the diagnosis process of male infertility. This research proposes a novel deep learning algorithm for malformation detection of sperm morphology using human sperm cell images.… read more here.
Keywords: human sperm; deep learning; method; novel deep ... See more keywords
Long-term cryostorage of semen in a human sperm bank does not affect clinical outcomes.
Sign Up to like & getrecommendations! Published in 2019 at "Fertility and sterility"
DOI: 10.1016/j.fertnstert.2019.06.008
Abstract: OBJECTIVE To evaluate the affect of the duration of donor sperm storage on pregnancy success among women undergoing assisted reproduction. DESIGN Retrospective cross-sectional study. SETTING Sperm bank. PATIENT(S) A total of 119,558 specimens retrieved using… read more here.
Keywords: sperm bank; clinical outcomes; human sperm; long term ... See more keywords
A technical note on the assessment of human sperm vitality using eosin-nigrosin staining.
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive biomedicine online"
DOI: 10.1016/j.rbmo.2020.03.002
Abstract: RESEARCH QUESTION How many spermatozoa and slides need to be counted to make a reliable assessment of sperm vitality? Currently, various authorities recommend assessing human sperm vitality on counts of at least 200 cells, but… read more here.
Keywords: eosin nigrosin; human sperm; 200 cells; vitality ... See more keywords
Anethole compromises human sperm function by affecting the sperm intracellular calcium concentration and tyrosine phosphorylation.
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive toxicology"
DOI: 10.1016/j.reprotox.2020.01.007
Abstract: Anethole is a natural anisole derivative that has been widely used in food and daily chemical industries, agricultural applications and the traditional medicine. It is closely related to aspects of daily life, and humans can… read more here.
Keywords: sperm function; tyrosine phosphorylation; anethole; human sperm ... See more keywords
Promescent Has a Cytotoxic Impact on Fresh Human Sperm In Vitro.
Sign Up to like & getrecommendations! Published in 2018 at "Urology"
DOI: 10.1016/j.urology.2017.12.027
Abstract: OBJECTIVE To assess the impact of Promescent, a commonly used topical medication for premature ejaculation (PE), on human sperm motility, forward progression (FP), viability, and sperm DNA fragmentation (SDF) in vitro. MATERIALS AND METHODS Aliquots… read more here.
Keywords: promescent cytotoxic; promescent; cytotoxic impact; human sperm ... See more keywords
Human sperm steer with second harmonics of the flagellar beat
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-01462-y
Abstract: Sperm are propelled by bending waves traveling along their flagellum. For steering in gradients of sensory cues, sperm adjust the flagellar waveform. Symmetric and asymmetric waveforms result in straight and curved swimming paths, respectively. Two… read more here.
Keywords: sperm steer; beat; human sperm; flagellar beat ... See more keywords