The Human Spleen in Malaria: Filter or Shelter?
Sign Up to like & getrecommendations! Published in 2020 at "Trends in parasitology"
DOI: 10.1016/j.pt.2020.03.001
Abstract: The human spleen is an immune sentinel and controls red blood cell (RBC) quality. By mechanically retaining subsets of infected RBCs, the spleen may reduce the pace at which the parasite biomass increases before the… read more here.
Keywords: malaria filter; filter shelter; human spleen; spleen ... See more keywords
Biomechanics of phagocytosis of red blood cells by macrophages in the human spleen
Sign Up to like & getrecommendations! Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2414437121
Abstract: Significance In the red pulp of the human spleen, senescent and altered red blood cells (RBCs) undergo prefiltration, filtration, and postfiltration. Previous research has shown how macrophages detect and engulf RBCs during prefiltration and how… read more here.
Keywords: red blood; phagocytosis; blood cells; biomechanics ... See more keywords