Loss of alpha‐globin genes in human subjects is associated with improved nitric oxide‐mediated vascular perfusion
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Hematology"
DOI: 10.1002/ajh.26058
Abstract: Alpha thalassemia is a hemoglobinopathy due to decreased production of the α‐globin protein from loss of up to four α‐globin genes, with one or two missing in the trait phenotype. Individuals with sickle cell disease… read more here.
Keywords: globin genes; globin; human subjects; globin gene ... See more keywords
Geospatial cryptography: enabling researchers to access private, spatially referenced, human subjects data for cancer control and prevention
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Geographical Systems"
DOI: 10.1007/s10109-017-0252-3
Abstract: Abstract As the volume, accuracy and precision of digital geographic information have increased, concerns regarding individual privacy and confidentiality have come to the forefront. Not only do these challenge a basic tenet underlying the advancement… read more here.
Keywords: subjects data; research; human subjects; cancer ... See more keywords
Learning to alternate
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Economics"
DOI: 10.1007/s10683-018-9568-1
Abstract: The Individual Evolutionary Learning (IEL) model explains human subjects’ behavior in a wide range of repeated games which have unique Nash equilibria. Using a variation of ‘better response’ strategies, IEL agents quickly learn to play… read more here.
Keywords: game; human subjects; learning alternate; nash equilibria ... See more keywords
Implications of circulating Meteorin-like (Metrnl) level in human subjects with type 2 diabetes.
Sign Up to like & getrecommendations! Published in 2018 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2017.11.031
Abstract: AIMS Meteorin-like (Metrnl) was recently identified as a novel adipomyokine induced by exercise and cold exposure. Metrnl improves glucose tolerance, increases systemic energy expenditure, induces white adipose browning, and promotes anti-inflammatory gene programs in obese/diabetic… read more here.
Keywords: human subjects; level; like metrnl; type diabetes ... See more keywords
Increased cytokine production by monocytes from human subjects who consumed grape powder was not mediated by differences in dietary intake patterns.
Sign Up to like & getrecommendations! Published in 2017 at "Nutrition research"
DOI: 10.1016/j.nutres.2017.03.001
Abstract: Recently, in a randomized, double-blind crossover study, we reported that consumption of grape powder by obese human subjects increased the production of the proinflammatory cytokines interleukin (IL)-1β and IL-6 by peripheral blood monocytes after ex… read more here.
Keywords: human subjects; grape powder; differences dietary; production ... See more keywords
[The Committee for the Protection of Human Subjects in biomedical research, crossroads of misunderstandings].
Sign Up to like & getrecommendations! Published in 2020 at "Therapie"
DOI: 10.1016/j.therap.2020.12.016
Abstract: The conditions for carrying out clinical experiments involved numerous and serious breaches of Hippocratic morality and of the rights of people subjected to research situations. The World Medical Association has recommended the prior intervention of… read more here.
Keywords: protection human; research; committee; human subjects ... See more keywords
Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-16436-w
Abstract: Cavernous angiomas (CA) are common vascular anomalies causing brain hemorrhage. Based on mouse studies, roles of gram-negative bacteria and altered intestinal homeostasis have been implicated in CA pathogenesis, and pilot study had suggested potential microbiome… read more here.
Keywords: human subjects; permissive microbiome; microbiome; neurovascular disease ... See more keywords
Biodistribution and radiation dosimetry of the positron emission tomography probe for AMPA receptor, [11C]K-2, in healthy human subjects
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-81002-3
Abstract: [11C]K-2, a radiotracer exhibiting high affinity and selectivity for α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs), is suitable for the quantification of AMPARs in living human brains and potentially useful in the identification of epileptogenic foci in… read more here.
Keywords: radiation dose; healthy human; human subjects; 11c healthy ... See more keywords
Elemental analysis in living human subjects using biomedical devices.
Sign Up to like & getrecommendations! Published in 2019 at "Physiological measurement"
DOI: 10.1088/1361-6579/ab6019
Abstract: Today, patients undergoing dialysis are at low risk for aluminum-induced dementia. Workers are unlikely to experience cadmium-induced emphysema and the public's exposure to lead is an order of magnitude lower than in 1970. The research… read more here.
Keywords: analysis living; human subjects; subjects using; analysis ... See more keywords
Chiral Pharmacokinetics and Metabolite Profile of Prolonged-release Ketamine Tablets in Healthy Human Subjects
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DOI: 10.1097/aln.0000000000003829
Abstract: Background: The anesthetic ketamine after intravenous dosing is nearly completely metabolized to R- and S-stereoisomers of the active norketamine (analgesic, psychoactive) and 2,6-hydroxynorketamine (potential analgesic, antidepressant) as well as the inactive dehydronorketamine. Oral administration favors… read more here.
Keywords: release ketamine; human subjects; ketamine tablets; prolonged release ... See more keywords
Fluorescein Aqueous Angiography in Live Normal Human Eyes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Glaucoma"
DOI: 10.1097/ijg.0000000000001042
Abstract: Purpose: To evaluate aqueous humor outflow (AHO) in intact eyes of live human subjects during cataract surgery using fluorescein aqueous angiography. Methods: Aqueous angiography was performed in 8 live human subjects (56 to 86 y old;… read more here.
Keywords: human subjects; live human; angiography; angiography live ... See more keywords