Articles with "human taar1" as a keyword



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Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies.

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Published in 2017 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2016.10.058

Abstract: Trace amines (TAs) are endogenous neuromodulators that play a functional role in the synaptic transmission within central nervous system (CNS), targeting trace amine-associated receptors (TAARs). Starting from our previous computational studies on TAAR1 and TAAR5… read more here.

Keywords: based derivatives; murine; biguanide based; taar1 agonists ... See more keywords