Ursodeoxycholyl lysophosphatidylethanolamide negatively regulates TLR‐mediated lipopolysaccharide response in human THP‐1‐derived macrophages
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2018.02.030
Abstract: Abstract The bile acid‐phospholipid conjugate ursodeoxycholyl oleoyl‐lysophophatidylethanolamide (UDCA‐18:1LPE) is an anti‐inflammatory and anti‐fibrotic agent as previously shown in cultured hepatocytes and hepatic stellate cells as well as in in vivo models of liver injury. We… read more here.
Keywords: anti inflammatory; response; udca 1lpe; derived macrophages ... See more keywords
1,4-Naphthoquinone Induces FcRn Protein Expression and Albumin Recycling in Human THP-1 Cells
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DOI: 10.1021/acsomega.3c01678
Abstract: The neonatal Fc receptor (FcRn) has been established as a major factor in regulating the metabolism of albumin and IgG in humans by protecting them from intracellular degradation after they are endocytosed into cells. We… read more here.
Keywords: protein expression; albumin recycling; expression; fcrn protein ... See more keywords
Comparative Proteomic Analysis of Polarized Human THP-1 and Mouse RAW264.7 Macrophages
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DOI: 10.3389/fimmu.2021.700009
Abstract: Macrophages can be polarized into classically activated macrophages (M1) and alternatively activated macrophages (M2) in the immune system, performing pro-inflammatory and anti-inflammatory functions, respectively. Human THP-1 and mouse RAW264.7 cell line models have been widely… read more here.
Keywords: thp mouse; raw264 macrophages; raw264; human thp ... See more keywords
Dynamic changes in human THP-1-derived M1-to-M2 macrophage polarization during Thelazia callipaeda MIF induction
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1078880
Abstract: Macrophages are innate immune cells with essential roles in the immune response during helminth infection. Particularly, the direction of macrophage polarization could contribute to pathogen trapping and killing as well as tissue repair and the… read more here.
Keywords: macrophage polarization; human thp; thelazia callipaeda; thp derived ... See more keywords
RNA Microarray-Based Comparison of Innate Immune Phenotypes between Human THP-1 Macrophages Stimulated with Two BCG Strains
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23094525
Abstract: Currently, the only available vaccine against tuberculosis is Mycobacterium bovis Bacille Calmette-Guérin (BCG). Pulmonary tuberculosis protection provided by the vaccine varies depending on the strain, the patient’s age and the evaluated population. Although the adaptive… read more here.
Keywords: immune responses; innate immune; human thp; bcg ... See more keywords