Development of a Highly Specific, Selective, and Sensitive Fluorescent Probe for Detection of Mycobacteria in Human Tissues
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202102640
Abstract: Tuberculosis (TB), including extrapulmonary TB, is responsible for more than one million deaths in a year worldwide. Existing methods of mycobacteria detection have poor sensitivity, selectivity, and specificity, especially in human tissues. Herein, the synthesis… read more here.
Keywords: probe detect; detect mycobacteria; detection; fluorescent probe ... See more keywords
Generating A Database of Phenotypic Consequences of Gene Regulation Across 40 Human Tissues
Sign Up to like & getrecommendations! Published in 2017 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2016.09.466
Abstract: Abstract GWAS and sequencing studies have yielded thousands of genetic variants robustly associated genetic complex traits. However, the underlying biology of those associations needs to be further elucidated. To address this problem we developed PrediXcan,… read more here.
Keywords: phenotypic consequences; human tissues; consequences gene; gene ... See more keywords
Genome-Wide Evaluation of Transcriptomic Responses of Human Tissues to Smoke: A Systems Biology Study.
Sign Up to like & getrecommendations! Published in 2022 at "Gene"
DOI: 10.1016/j.gene.2021.146114
Abstract: The harmful compounds in various sources of smoke threaten human health. So far, many studies have investigated the effects of compounds of smoke on transcriptome changes in different human tissues. However, no study has been… read more here.
Keywords: cells tissues; human tissues; gene; target ... See more keywords
Landscape of SARS-CoV-2 spike protein-interacting cells in human tissues
Sign Up to like & getrecommendations! Published in 2021 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2021.107567
Abstract: Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global pandemic. However, the mechanism of tissue tropism of SARS-CoV-2 remains unclear. Here, recombinant receptor-binding subdomain 1 of spike… read more here.
Keywords: human tissues; spike protein; sars cov; marrow cells ... See more keywords
Molecular characterization of novel Adeno-associated virus variants infecting human tissues.
Sign Up to like & getrecommendations! Published in 2019 at "Virus research"
DOI: 10.1016/j.virusres.2019.197716
Abstract: Despite the many advantages with Adeno-associated virus (AAV) based vectors for gene therapy, certain barriers related to host permissivity and immune response precludes their widespread application in humans. A comprehensive study of the distribution and… read more here.
Keywords: dna; human tissues; associated virus; adeno associated ... See more keywords
Corrigendum: Landscape of X chromosome inactivation across human tissues
Sign Up to like & getrecommendations! Published in 2018 at "Nature"
DOI: 10.1038/nature25993
Abstract: This corrects the article DOI: 10.1038/nature24265 read more here.
Keywords: landscape chromosome; human tissues; inactivation across; corrigendum landscape ... See more keywords
Systematic analysis of gene expression patterns associated with postmortem interval in human tissues
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-05882-0
Abstract: Postmortem mRNA degradation is considered to be the major concern in gene expression research utilizing human postmortem tissues. A key factor in this process is the postmortem interval (PMI), which is defined as the interval… read more here.
Keywords: pmi; human tissues; gene expression; expression ... See more keywords
Cryopreservation of Viable Human Tissues: Renewable Resource for Viable Tissue, Cell Lines, and Organoid Development.
Sign Up to like & getrecommendations! Published in 2020 at "Biopreservation and biobanking"
DOI: 10.1089/bio.2019.0062
Abstract: The availability of viable human tissues is critical to support translational research focused on personalized care. Most studies have relied on fresh frozen or formalin-fixed paraffin-embedded tissues for histopathology, genomics, and proteomics. Yet, basic, translational,… read more here.
Keywords: human tissues; tissue; viable human; viable tissue ... See more keywords
HeRA: an atlas of enhancer RNAs across human tissues
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa940
Abstract: Abstract Enhancer RNA (eRNA) is a type of long non-coding RNA transcribed from DNA enhancer regions. Despite critical roles of eRNA in gene regulation, the expression landscape of eRNAs in normal human tissue remains unexplored.… read more here.
Keywords: tissues hera; human tissues; expression; across human ... See more keywords
IntroVerse: a comprehensive database of introns across human tissues
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac1056
Abstract: Abstract Dysregulation of RNA splicing contributes to both rare and complex diseases. RNA-sequencing data from human tissues has shown that this process can be inaccurate, resulting in the presence of novel introns detected at low… read more here.
Keywords: introns across; introverse comprehensive; database introns; introverse ... See more keywords
The DifferentialNet database of differential protein–protein interactions in human tissues
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx981
Abstract: Abstract DifferentialNet is a novel database that provides users with differential interactome analysis of human tissues (http://netbio.bgu.ac.il/diffnet/). Users query DifferentialNet by protein, and retrieve its differential protein–protein interactions (PPIs) per tissue via an interactive graphical… read more here.
Keywords: protein; protein interactions; human tissues; protein protein ... See more keywords