Genomic variants reveal differential evolutionary constraints on human transglutaminases and point towards unrecognized significance of transglutaminase 2
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DOI: 10.1371/journal.pone.0172189
Abstract: Transglutaminases (TGMs) catalyze Ca2+-dependent transamidation of proteins with specified roles in blood clotting (F13a) and in cornification (TGM1, TGM3). The ubiquitous TGM2 has well described enzymatic and non-enzymatic functions but in-spite of numerous studies its… read more here.
Keywords: reveal differential; tgm2; human transglutaminases; genomic variants ... See more keywords