Abstract 1636: Generation of novel potent human TREX1 inhibitors facilitated by crystallography
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DOI: 10.1158/1538-7445.am2023-1636
Abstract: Background: STING is an innate immune sensor critical for the development of immunity. Tumor cells can inactivate the STING pathway to avoid immune recognition, emphasizing its importance in generating tumor-specific immunity. Broad activation of STING… read more here.
Keywords: generation novel; crystallography; trex1 inhibitors; tumor ... See more keywords