Functional characterization of the human tRNA methyltransferases TRMT10A and TRMT10B
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa353
Abstract: Abstract The TRM10 family of methyltransferases is responsible for the N1-methylation of purines at position 9 of tRNAs in Archaea and Eukarya. The human genome encodes three TRM10-type enzymes, of which only the mitochondrial TRMT10C… read more here.
Keywords: trmt10b; functional characterization; characterization human; trmt10a trmt10b ... See more keywords
Human tRNA-Derived Small RNAs Modulate Host–Oral Microbial Interactions
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DOI: 10.1177/0022034518770605
Abstract: Coevolution of the human host and its associated microbiota has led to sophisticated interactions to maintain a delicate homeostasis. Emerging evidence suggests that in addition to small molecules, peptides, and proteins, small regulatory noncoding RNAs… read more here.
Keywords: derived small; trna derived; tsrna; small rnas ... See more keywords
Molecular architecture of the human tRNA ligase complex
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DOI: 10.7554/elife.71656
Abstract: RtcB enzymes are RNA ligases that play essential roles in tRNA splicing, unfolded protein response, and RNA repair. In metazoa, RtcB functions as part of a five-subunit tRNA ligase complex (tRNA-LC) along with Ddx1, Cgi-99,… read more here.
Keywords: trna ligase; ligase complex; molecular architecture; human trna ... See more keywords