Human Endometrial Extracellular Vesicles Functionally Prepare Human Trophectoderm Model for Implantation: Understanding Bidirectional Maternal‐Embryo Communication
Sign Up to like & getrecommendations! Published in 2019 at "PROTEOMICS"
DOI: 10.1002/pmic.201800423
Abstract: Embryo implantation into maternal endometrium is critical for initiation and establishment of pregnancy, requiring developmental synchrony between endometrium and blastocyst. However, factors regulating human endometrial–embryo cross talk and facilitate implantation remain largely unknown. Extracellular vesicles… read more here.
Keywords: extracellular vesicles; human endometrial; embryo; human trophectoderm ... See more keywords
Human Trophectoderm Spheroid Derived from Human Embryonic Stem Cells.
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DOI: 10.1007/7651_2021_460
Abstract: The use of human embryos for studying the early implantation processes and trophoblast is restricted by ethical concerns. The development of models mimicking the peri-implantation embryos is critical for understanding the physiology of human embryos… read more here.
Keywords: derived human; human embryonic; human trophectoderm; stem cells ... See more keywords
VGLL1 cooperates with TEAD4 to control human trophectoderm lineage specification
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DOI: 10.1038/s41467-024-44780-8
Abstract: Authors report that VGLL1 regulates cell fate determination and self-renewal of human pluripotent stem cell-derived trophectoderm-like cells and trophoblast stem cells via modulation of chromatin accessibility in cooperation with TEAD4. In contrast to rodents, the… read more here.
Keywords: human trophectoderm; stem cells; specification; cooperates tead4 ... See more keywords