Structures and gating mechanism of human TRPM2
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DOI: 10.1126/science.aav4809
Abstract: Architecture of the human TRPM2 channel Adenosine diphosphate–ribose (ADPR) mediates calcium (Ca2+) release by activating the transient receptor potential melastatin 2 (TRPM2) channel. Three structures now elucidate the conformational regulation mechanism of TRPM2 gating. Wang… read more here.
Keywords: adpr; human trpm2; mechanism; channel ... See more keywords