Identification of a binding site for small molecule inhibitors targeting human TRPM4
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DOI: 10.1038/s41467-025-56131-2
Abstract: Transient receptor potential (TRP) melastatin 4 (TRPM4) protein is a calcium-activated monovalent cation channel associated with various genetic and cardiovascular disorders. The anthranilic acid derivative NBA is a potent and specific TRPM4 inhibitor, but its… read more here.
Keywords: binding site; site small; human trpm4; trpm4 ... See more keywords