Cryo-EM Structure and Activator Screening of Human Tryptophan Hydroxylase 2
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DOI: 10.3389/fphar.2022.907437
Abstract: Human tryptophan hydroxylase 2 (TPH2) is the rate-limiting enzyme in the synthesis of serotonin. Its dysfunction has been implicated in various psychiatric disorders such as depression, autism, and bipolar disorder. TPH2 is typically decreased in… read more here.
Keywords: human tryptophan; cryo structure; structure; tph2 ... See more keywords