Articles with "human u937" as a keyword



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Anti-Inflammatory Effects of Four Psilocybin-Containing Magic Mushroom Water Extracts in vitro on 15-Lipoxygenase Activity and on Lipopolysaccharide-Induced Cyclooxygenase-2 and Inflammatory Cytokines in Human U937 Macrophage Cells

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Published in 2021 at "Journal of Inflammation Research"

DOI: 10.2147/jir.s317182

Abstract: Purpose During a pathological inflammation, macrophages are activated to produce accumulation of inflammatory mediators such as induced-cyclooxygenase-2 (COX-2), 15-lipoxygenase (15-LOX) and pro-inflammatory cytokines. Pathological inflammation is a significant problem in many chronic diseases. As a… read more here.

Keywords: psilocybin containing; water; anti inflammatory; activity ... See more keywords
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Synthetic chalcone derivatives inhibit cytokine secretion via inhibition of ERK and JNK pathways in human U937 macrophage

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Published in 2021 at "Tropical Journal of Pharmaceutical Research"

DOI: 10.4314/tjpr.v18i4.11

Abstract: Purpose: To investigate the inhibitory effects of a chalcone derivative on lipopolysaccharide (LPS)induced interleukin (IL)-6 and IL-8 secretions and on LPS-induced mitogen-activated protein kinases (MAPK) and nuclear factor kappa B (NF-κB) activation in human U937… read more here.

Keywords: via inhibition; secretion; inhibition erk; u937 macrophage ... See more keywords