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Published in 2021 at "Biomolecular NMR assignments"
DOI: 10.1007/s12104-021-10024-9
Abstract: The human UDP-glucuronosyltransferase (UGT) family of enzymes catalyze the covalent addition of glucuronic acid to a wide range of compounds, generally rendering them inactive. Although important for clearance of environmental toxins and metabolites, UGT activation…
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Keywords:
13c 15n;
human udp;
terminal domain;
udp glucuronosyltransferase ... See more keywords
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Published in 2018 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2018.02.009
Abstract: Amentoflavone (AMF), an abundant natural biflavonoid found in many medicinal plants, displays various beneficial effects including anti-inflammatory, anti-oxidative and anti-cancer. Despite the extensive studies on pharmacological activities, the toxicity or undesirable effects of AMF are…
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Keywords:
inhibitor;
inhibitor human;
udp glucuronosyltransferases;
inhibition ... See more keywords
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Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24021454
Abstract: Gypensapogenin C (GPC) is one of the important aglycones of Gynostemma pentaphyllum (GP), which is structurally glucuronidated and is highly likely to bind to UGT enzymes in vivo. Due to the important role of glucuronidation…
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Keywords:
human udp;
glucuronidation;
udp glucuronosyltransferase;
gpc ... See more keywords