Articles with "human udp" as a keyword



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1H, 13C and 15N chemical shift assignments of the C-terminal domain of human UDP-Glucuronosyltransferase 2B7 (UGT2B7-C).

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Published in 2021 at "Biomolecular NMR assignments"

DOI: 10.1007/s12104-021-10024-9

Abstract: The human UDP-glucuronosyltransferase (UGT) family of enzymes catalyze the covalent addition of glucuronic acid to a wide range of compounds, generally rendering them inactive. Although important for clearance of environmental toxins and metabolites, UGT activation… read more here.

Keywords: 13c 15n; human udp; terminal domain; udp glucuronosyltransferase ... See more keywords
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Amentoflavone is a potent broad-spectrum inhibitor of human UDP-glucuronosyltransferases.

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Published in 2018 at "Chemico-biological interactions"

DOI: 10.1016/j.cbi.2018.02.009

Abstract: Amentoflavone (AMF), an abundant natural biflavonoid found in many medicinal plants, displays various beneficial effects including anti-inflammatory, anti-oxidative and anti-cancer. Despite the extensive studies on pharmacological activities, the toxicity or undesirable effects of AMF are… read more here.

Keywords: inhibitor; inhibitor human; udp glucuronosyltransferases; inhibition ... See more keywords
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Identification of Human UDP-Glucuronosyltransferase Involved in Gypensapogenin C Glucuronidation and Species Differences

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24021454

Abstract: Gypensapogenin C (GPC) is one of the important aglycones of Gynostemma pentaphyllum (GP), which is structurally glucuronidated and is highly likely to bind to UGT enzymes in vivo. Due to the important role of glucuronidation… read more here.

Keywords: human udp; glucuronidation; udp glucuronosyltransferase; gpc ... See more keywords