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Human UFSP1 is an active protease that regulates UFM1 maturation and UFMylation

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2 Published in 2022 at "Cell Reports"

DOI: 10.1101/2022.02.28.482207

Abstract: An essential first step in the posttranslational modification of proteins with UFM1, UFMylation, is the proteolytic cleavage of pro-UFM1 to expose a C-terminal glycine. Of the two UFM1-specific proteases (UFSPs) identified in humans, only UFSP2… read more here.

Keywords: ufm1 maturation; protease; human ufsp1; ufmylation ... See more keywords