In vitro inhibition of human UGT isoforms by ritonavir and cobicistat
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DOI: 10.1080/00498254.2017.1370655
Abstract: Abstract 1. Ritonavir and cobicistat are pharmacokinetic boosting agents used to increase systemic exposure to other antiretroviral therapies. The manufacturer’s data suggests that cobicistat is a more selective CYP3A4 inhibitor than ritonavir. However, the inhibitory effect… read more here.
Keywords: ritonavir cobicistat; human ugt; ugt isoforms; inhibition human ... See more keywords